[P199] Epithelioid cell histiocytoma developed on palm = [P199] Epithelioid cell histiocytoma developed on palm

다국어 초록 (Multilingual Abstract)

Fibrous histiocytoma is the most common cutaneous soft tissue lesions mainly located on the limbs and present as small, hyperkeratotic, cutaneous nodules. Epithelioid cell histiocytoma is one of the several variants of fibrous histiocytoma. Histologically, it is characterized as a well demarcated lesion composed of large epithelioid cells in the papillary and superficial reticular dermis. A49-year-old male presented with slowly increased mass on the left palm during 3 months. The physical examination revealed a well demarcated 1 x 1 cm sized dark brownish to flesh colored protruded mass on the left palm. Histopathologic examination revealed an infiltration of the papillary dermis by polygonal epithelioid cells with abundant eosinophilic cytoplasm. Lesional tissue was enclosed by collarettes of surface epithelium. There were abundant small blood vessels and a few multinucleated giant cells. Immunohistochemical study revealed that epithelioid cells were positive for CD31, CD68 and negative for S-100, CK AE1/3, CD1, CD34. Based onthese findings, he was diagnosed with epithelioid cell histiocytoma. The lesion was completely excised. Epithelioid cell histiocytoma has a broad differential diagnosis. Therefore, we should consider the histological features with immunohistochemical studies to diagnose epithelioid cell histiocytoma. We report a rare epitheloid cell histiocytoma located in the left palm, which is occurred in unusual site.