Comparison between two progesterone sources and two oestradiol formulations in a Heatsynch protocol for postpartum cycling dairy cows in pasture

다국어 초록 (Multilingual Abstract)

To compare an injectable progesterone (MAD-4) with an intravaginal device (IPD), and natural O17 with synthetic oestradiol (OB) in a synchronisation protocol, 51 cows were divided into four groups. Each group was treated with one of the two sources of progesterone and one of the two oestradiol formulations. Oestrus behaviour, follicle diameter, and pregnancy rates were evaluated. Oestrus behaviour (p =0.902), numbers of cows in oestrus (p = 0.917), follicle diameter (p = 0.416), and pregnancy rates (p = 0.873) were similar among the four groups. More cows in the group treated with the IPD and OB scored ＞ 200 oestrus behaviour points compared to the other groups (p = 0.038).
A longer interval between the end of treatment and oestrus was observed among cows treated with MAD-4 than cows given the IPD (p = 0.030), but no differences were found between animals receiving the two oestradiol formulations (OB and O17). While the use of MAD-4 requires further testing, similar responses to natural oestradiol observed in the present study could allow the use of this formulation in reproductive protocols because it is not associated with the potential human health risks of OB.

참고문헌 (Reference)

1 Roelofs JB., "Various behavioral signs of and their relationship with time of ovulation in dairy cattle" 63 : 1366-1377, 2005

2 Cavestany D., "Use of medroxyprogesterone acetate(MAP)in lactating Holstein cows within an Ovsynch protocol : follicular growth and hormonal patterns" 59 : 1787-1798, 2003

3 Pancarci SM., "Use of estradiol cypionate in a presynchronized timed artificial insemination program for lactating dairy cattle" 85 : 122-131, 2002

4 Tenhagen BA., "Use of Ovsynch in dairy herds-differences between primiparous and multiparous cows" 81 : 1-11, 2004

5 Mateus L., "Treatment of unobserved oestrus in a dairy cattle herd with low oestrus detection rate up to 60 days post-partum" 37 : 57-60, 2002

6 Lucy MC, "The use of hormonal treatments to improve the reproductive performance of lactating dairy cows in feedlot or pasture-based management systems" 82 : 495-512, 2004

7 Alexander TJ., "The influence of the stage of the estrous cycle and novel cows upon mounting activity of dairy cattle" 59 : 1430-1439, 1984

8 Van Eerdenburg FJCM., "The Relationship between estrous behavioral score and time of ovulation in dairy cattle" 85 : 1150-1156, 2002

9 Walsh RB., "Synchronization of estrus and pregnancy risk in anestrous dairy cows after treatment with a progesteronereleasing intravaginal device" 90 : 1139-1148, 2007

10 Bartolome JA., "Synchronization and resynchronization of inseminations in lactating dairy cows with the CIDR insert and the Ovsynch protocol" 72 : 869-878, 2009

11 Pennington JA., "Relationships of sexual activities in estrus cows to different frequencies of observation and pedometer measurements" 69 : 2925-2934, 1986

12 Macmillan KL, "Recent advances in the synchronisation of estrus and ovulation in dairy cows" 56 : 42-47, 2010

13 Maatje K., "Predicting optimal time of insemination in cows that show visual signs of estrus by estimating onset of estrus with pedometers" 80 : 1098-1105, 1997

14 Peter AT., "Postpartum ovarian activity in dairy cows: correlation between behavioral estrus, pedometer measurements and ovulations" 26 : 111-115, 1986

15 Grosshans T., "Performance and genetic parameters for fertility of seasonal dairy cows in New Zealand" 51 : 41-51, 1997

16 López-Gatius F., "Ovulation failure and double ovulation in dairy cattle : risk factors and effects" 63 : 1298-1307, 2005

17 Ahmed WM, "Overview on some factors negatively affecting ovarian activity in large farm animals" 1 : 53-66, 2007

18 Lehrer AR., "Oestrus detection in cattle : recent developments" 28 : 355-361, 1992

19 Esslemont RJ., "Oestrus behaviour in a herd of dairy cows" 99 : 472-475, 1976

20 Chenault JR., "Intravaginal progesterone insert to synchronize return to estrus of previously inseminated dairy cows" 86 : 2039-2049, 2003

21 Stevenson JS., "Inseminations at estrus induced by presynchronization before application of synchronized estrus and ovulation" 88 : 399-405, 2005

22 Roelofs JB., "Influence of repeated rectal ultrasound examinations on hormone profiles and behaviour around oestrus and ovulation in dairy cattle" 62 : 1337-1352, 2004

23 Lammoglia MA., "Induced and synchronized estrus in cattle : dose titration of estradiol benzoate in peripubertal heifers and postpartum cows after treatment with an intravaginal progesterone-releasing insert and prostaglandin F2α" 76 : 1662-1670, 1998

24 Nation DP., "Hormonal and ovarian responses to a 5-day progesterone treatment in anoestrous dairy cows in the third week post-partum" 63 : 13-25, 2000

25 Kasimanickam R., "Fertility following fixed time AI or insemination at observed estrus in Ovsynch and Heatsynch programs in lactating dairy cows" 63 : 2550-2559, 2005

26 Cavestany D., "Evaluation of two different oestrus-synchronization methods with timed artificial insemination and resynchronization of returns to oestrus in lactating Holstein cows" 77 : 141-155, 2003

27 Cavestany D, "Estradiol and progesterone profiles in an oestrus synchronization protocol in Holstein cows. 16th ed" World Buiatrics Congress 14-18, 2010

28 Villarroel A., "Effect of post-insemination supplementation with PRID on pregnancy in repeat-breeder Holstein cows" 61 : 1513-1520, 2004

29 Van Eerdenburg FJCM., "Detection of oestrus in dairy cows : a new approach to an old problem" 18 : 52-54, 1996

30 Melendez P., "Comparison of two estrus-synchronization protocols and timed artificial insemination in dairy cattle" 89 : 4567-4572, 2006

31 Ryan DP., "Comparison of oestrus synchronisation regimens for lactating dairy cows" 56 : 153-168, 1999

32 Cavestany D, "Comparación entre dos fuentes de progesterona (dispositivo intravaginal o inyectable subcutánea) incluidas en un protocolo de sincronización de ovulaciones en vacas Holando posparto, tratadas en fase folicular o luteal del ciclo estral. 15th ed" Paysandú 258-259, 2011

33 Dobson H., "A conceptual model of the influence of stress on female reproduction" 125 : 151-163, 2003

34 Edmonson AJ., "A body condition scoring chart for Holstein dairy cows" 72 : 68-78, 1989