즉시 탈회 치아이식재를 사용한 치조골 재건술

다국어 초록 (Multilingual Abstract)

Ideal autogenous or allogenic bone graft materials should provide 1) stabilization of blood clot, 2) scaffolds for cellular proliferation and differentiation, 3) release of osteogenic growth factors, 4) appropriate resorption profile for remodeling of new bone. Teeth, especially dentin, mostly contain hydroxyapatite and type I collagen which are similar to bone, and could be valuable graft material. Clinically teeth are used as calcined or demineralized forms.
Demineralized form of dentin can be more effective as a graft material. But a conventional decalcification method takes time and long treatment time may give negative effects to various osteogenic proteins in dentin. Author used a new clinical method to prepare autogenous teeth, which could be grafted into the removal defects immediately after extraction using vacuum ultrasonic system. The process could be finished within two hours regardless of the form (powder, chip or block). Teeth were processed to graft materials in block, chip, or powder types immediately after extraction. It took 120 minutes to prepare block types and 40 minutes to prepare powder. Clinical cases did not show any adverse response and the healing was favorable. Rapid preparation of autogenous teeth with the vacuum ultrasonic system could make the immediate one-day extraction and graft possible.

목차 (Table of Contents)

• ABSTRACT
• Ⅰ. 서론
• Ⅱ. 즉시 탈회 치아이식재를 위한 치아 전처리 단계
• Ⅲ. 즉시 탈회 치아이식재의 처리 방법
• Ⅳ. 즉시 탈회 치아이식재의 임상증례
• Ⅴ. 총괄 및 고안
• Ⅵ. 결론
• 참고문헌

참고문헌 (Reference)

1 김은석, "Various autogenous fresh demineralized tooth forms for alveolar socket preservation in anterior tooth extraction sites: a series of 4 cases" 대한악안면성형재건외과학회 37 (37): 1-7, 2015

2 Huggins C, "Transformation of fibroblasts by allogeneic and xenogeneic transplants of demineralized tooth and bone" 132 (132): 1250-1258, 1970

3 이은영, "Scanning Electron Microscopy and Energy Dispersive X-ray Spectroscopy Studies on Processed Tooth Graft Material by Vacuum-ultrasonic Acceleration" 대한악안면성형재건외과학회 36 (36): 103-110, 2014

4 Kim SG, "Grafting of large defects of the jaws with a particulate dentinplaster of Paris combination" 88 (88): 22-25, 1999

5 Leslie HW, "Donation, Banking, and Transplantation of Allograft Tissues" 24 (24): 891-905, 1989

6 Yamaguchi K, "Degradation-resistant character of synthetic hydroxyapatite block filled in bone defects" 16 (16): 983-985, 1995

7 Hall BK, "Bone matrix and bone specific products" CRC Press 1-, 1991

8 Yeomans JD, "Bone induction by decalcified dentine implanted into oral, osseous and muscles tissues" 12 (12): 999-1008, 1967

9 Yeomans JD, "Bone induction by decalcified dentine implanted into oral, osseous and muscle tissues" 12 (12): 999-1008, 1967

10 Pietrzak WS, "BMP depletion occurs during prolonged acid demineralization of bone: characterization and implications for graft preparation" 12 (12): 81-88, 2011

11 Ito K, "Analysis of bone morphogenetic protein in human dental pulp tissues" 8 : 166-169, 2008

12 Kounadi E, "An electron microscopic study of collagen fibril structure after lithium treatment-II. The effects of low lithium dose and short treatment on mouth skin collagen" 26 (26): 113-120, 1995