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      면역글로불린과 Leflunomide로 치료한 BK 바이러스 신병증 = Nephrology A Case of Combining Intravenous Immunoglobulin and Leflunomide for BK Nephropathy

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      https://www.riss.kr/link?id=A82672022

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      BK virus nephropathy has emerged as an important cause of renal allograft dysfunction. It affects 1-10% of renal transplant patients and results in significant graft dysfunction in more than 50% of cases. A reduction in the amount of immunosuppressant...

      BK virus nephropathy has emerged as an important cause of renal allograft dysfunction. It affects 1-10% of renal transplant patients and results in significant graft dysfunction in more than 50% of cases. A reduction in the amount of immunosuppressants is not an appropriate treatment option for advanced stage BK nephropathy; therefore, other treatment strategies need to be considered such as cidofovir, leflunomide, and intravenous immunoglobulin (IVIG) in combination with reduced immunosuppression. The use of IVIG may be a valuable treatment option in patients with BK virus nephropathy. We report our experience with IVIG rescue therapy in a patient and the progression of BK nephropathy despite leflunomide therapy. (Korean J Med 2011;81:512-516)

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      참고문헌 (Reference)

      1 손영기, "신장이식 후 BK 바이러스 관련 신병증에서의 leflunomide의 임상경험" 대한신장학회 28 (28): 211-218, 2009

      2 Josephson MA, "Treatment of renal allograft polyoma BK virus infection with leflunomide" 81 : 704-710, 2006

      3 Hirsch HH, "Polyomavirusassociated nephropathy in renal transplantation: interdisciplinary analyses and recommendations" 79 : 1277-1286, 2005

      4 Binet I, "Polyomavirus disease under new immunosuppressive drugs: a cause of renal graft dysfunction and graft loss" 67 : 918-922, 1999

      5 Faguer S, "Leflunomide treatment for polyomavirus BK-associated nephropathy after kidney transplantation" 20 : 962-969, 2007

      6 Williams JW, "Leflunomide for polyomavirus type BK nephropathy" 352 : 1157-1158, 2005

      7 Sener A, "Intravenous immunoglobulin as a treatment for BK virus associated nephropathy: one-year follow-up of renal allograft recipients" 81 : 117-120, 2006

      8 Waldman WJ, "Inhibition of cytomegalovirus in vitro and in vivo by the experimental immunosuppressive agent leflunomide" 42 : 412-418, 1999

      9 Brennan DC, "Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reduction" 5 : 582-594, 2005

      10 Leca N, "Higher levels of leflunomide are associated with hemolysis and are not superior to lower levels for BK virus clearance in renal transplant patients" 3 : 829-835, 2008

      1 손영기, "신장이식 후 BK 바이러스 관련 신병증에서의 leflunomide의 임상경험" 대한신장학회 28 (28): 211-218, 2009

      2 Josephson MA, "Treatment of renal allograft polyoma BK virus infection with leflunomide" 81 : 704-710, 2006

      3 Hirsch HH, "Polyomavirusassociated nephropathy in renal transplantation: interdisciplinary analyses and recommendations" 79 : 1277-1286, 2005

      4 Binet I, "Polyomavirus disease under new immunosuppressive drugs: a cause of renal graft dysfunction and graft loss" 67 : 918-922, 1999

      5 Faguer S, "Leflunomide treatment for polyomavirus BK-associated nephropathy after kidney transplantation" 20 : 962-969, 2007

      6 Williams JW, "Leflunomide for polyomavirus type BK nephropathy" 352 : 1157-1158, 2005

      7 Sener A, "Intravenous immunoglobulin as a treatment for BK virus associated nephropathy: one-year follow-up of renal allograft recipients" 81 : 117-120, 2006

      8 Waldman WJ, "Inhibition of cytomegalovirus in vitro and in vivo by the experimental immunosuppressive agent leflunomide" 42 : 412-418, 1999

      9 Brennan DC, "Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reduction" 5 : 582-594, 2005

      10 Leca N, "Higher levels of leflunomide are associated with hemolysis and are not superior to lower levels for BK virus clearance in renal transplant patients" 3 : 829-835, 2008

      11 Lee JS, "Effect of high dose intravenous immunoglobulins on the treatment of antibody mediated humoral rejection and BK virus infection in renal transplant recipients" 21 : 140-142, 2007

      12 Howell DN, "Diagnosis and management of BK polyomavirus interstitial nephritis in renal transplant recipients" 68 : 1279-1288, 1999

      13 Randhawa P, "BK virus infection in transplant recipients: an overview and update" 6 : 2000-2005, 2006

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 계속평가 신청대상 (계속평가)
      2021-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
      2018-12-01 평가 등재후보 탈락 (계속평가)
      2017-12-01 평가 등재후보로 하락 (계속평가) KCI등재후보
      2013-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-05-15 학술지명변경 외국어명 : Korean Journal of Medicine -> The Korean Journal of Medicine KCI등재
      2006-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2003-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2002-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2000-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.1 0.1 0.1
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.11 0.1 0.259 0.02
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