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      Dietary intake estimation of PCDD/Fs via milk and meat consumption in Korean population using the probabilistic model

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      https://www.riss.kr/link?id=A108394214

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      다국어 초록 (Multilingual Abstract)

      The objective of this study is to estimate the dietary exposure of polychlorinated dibenzo-p-dioxins and dibezofurans (PCDD/Fs) of Korean population via milk and meat using a probabilistic exposure assessment model. Total 319 raw milk and meat samples...

      The objective of this study is to estimate the dietary exposure of polychlorinated dibenzo-p-dioxins and dibezofurans (PCDD/Fs) of Korean population via milk and meat using a probabilistic exposure assessment model. Total 319 raw milk and meat samples collected in the period 2006-2008 from nationwide Korea were measured the concentrations of 17 PCDD/Fs. Distributions of dietary exposure of 7 age subgroups to PCDD/Fs from the commodities were estimated probabilistically using Monte Carlo simulations.
      Dietary exposure groups were divided as lower, medium and high consumer subgroups according to the consumption of each commodity. The amounts of dietary exposures of Korean population subgroups were compared to the provisional maximum tolerable monthly intake (PTMI) recommended by the Joint FAO/WHO Expert Committee on Food Additives and Contaminants (JECFA). The mean PCDD/Fs concentrations in raw milk and meat of beef, prok and chicken were measured as 0.501, and 0.022~0.150pg WHO-TEQ/g, respectively. Dietary exposure of children was significantly higher than that of adults due to their high milk consumption per body weight (BW). Dietary intake of PCDD/Fs of the Korean populations estimated ranged from 0.154 to 1.248 pg WHO- TEQ/kg BW/day for high consumers (the 97.5th percentile) at the upper bound. Dietary intakes of average population of various subgroups were below the half of PTMI, but those of higher consumers were found exceeding or comparable to PTMI at the upper bound level. This study also suggests that the estimated PCDD/Fs concentrations in milk and meat are comparable to those reported in previous studies.
      Probabilistic assessment model for PCDD/Fs exposure in meat and milk commodities could be used to estimate the exposure of PCDD/Fs in Korean population for the development of risk mangement mesaures for PCDD/Fs in meat and milk.

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      참고문헌 (Reference) 논문관계도

      1 JECFA, 24-40, 2001

      2 Tsutsumi T, "Update of daily intake of PCDDs, PCDFs, and dioxin-like PCBs from food in Japan" 45 (45): 1129-1137, 2001

      3 Fingerhut MA, "The epidemiology of populations exposed to dioxin" (108) : 31-50, 1991

      4 KCDC, "The Fourth Korea National Health and Nutrition Examination Survey(KNHANES Ⅳ-3)"

      5 Llobet JM, "Significant decreasing trend in human dietary exposure to PCDD/PCDFs and PCBs in Catalonia, Spain" 178 (178): 117-126, 2008

      6 Parzefall W, "Risk assessment of dioxin contamination in human food" 40 (40): 1185-1189, 2002

      7 EFSA, "Results of the monitoring of dioxin levels in food and feed" 8 (8): 36-, 2010

      8 Kim M, "Relationship of PCDD/Fs congener profiles between beef and raw milk in South Korea" 70 (70): 1563-1567, 2008

      9 WHO, "Re-evaluation of human and mammalian toxic equivalency factors (TEFs)"

      10 JECFA, "Polychlorinatd dibenzodioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls in Safety evaluation of certain contaminants in food" 48 : 16-, 2002

      1 JECFA, 24-40, 2001

      2 Tsutsumi T, "Update of daily intake of PCDDs, PCDFs, and dioxin-like PCBs from food in Japan" 45 (45): 1129-1137, 2001

      3 Fingerhut MA, "The epidemiology of populations exposed to dioxin" (108) : 31-50, 1991

      4 KCDC, "The Fourth Korea National Health and Nutrition Examination Survey(KNHANES Ⅳ-3)"

      5 Llobet JM, "Significant decreasing trend in human dietary exposure to PCDD/PCDFs and PCBs in Catalonia, Spain" 178 (178): 117-126, 2008

      6 Parzefall W, "Risk assessment of dioxin contamination in human food" 40 (40): 1185-1189, 2002

      7 EFSA, "Results of the monitoring of dioxin levels in food and feed" 8 (8): 36-, 2010

      8 Kim M, "Relationship of PCDD/Fs congener profiles between beef and raw milk in South Korea" 70 (70): 1563-1567, 2008

      9 WHO, "Re-evaluation of human and mammalian toxic equivalency factors (TEFs)"

      10 JECFA, "Polychlorinatd dibenzodioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls in Safety evaluation of certain contaminants in food" 48 : 16-, 2002

      11 Kiviranta H, "Market basket study on dietary intake of PCDD/Fs, PCBs, and PBDEs in Finland" 30 (30): 923-932, 2004

      12 Kim Y, "Levels of PCDDs and PCDFs in two kinds of fast foods in Korea" 43 (43): 851-855, 2001

      13 Esposito M, "Levels and congener profiles of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like polychlorinated biphenyls in cow's milk collected in Campania, Italy" 77 (77): 1212-1216, 2009

      14 Schecter A, "Intake of dioxins and related compounds from food in the U. S. population" 63 (63): 1-18, 2001

      15 Wang IC, "Human dietary exposure to polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in Taiwan" 164 (164): 621-626, 2009

      16 EFSA, "Guidance of the scientific committee on a request from EFSA related to uncertainties in dietary exposure assessment" 438 : 1-54, 2006

      17 Liem AK, "Exposure of populations to dioxins and related compounds" 17 (17): 241-259, 2000

      18 SCF, "European Commission, Brussels, Update based on new scientific information available since the adoption of the SCF opinion of 22"

      19 Sasamoto T, "Estimation of 1999-2004 dietary daily intake of PCDDs, PCDFs and dioxin-like PCBs by a total diet study in metropolitan Tokyo, Japan" 64 (64): 634-641, 2006

      20 Schecter A, "Dioxins in U. S. food and estimated daily intake" 29 (29): 2261-2265, 1994

      21 Moon HB, "Dietary intake of PCDDs, PCDFs and dioxin-like PCBs, due to the consumption of various marine organisms from Korea" 62 (62): 1142-1152, 2006

      22 Windal I, "Dietary intake of PCDD/Fs and dioxin-like PCBs of the Belgian population" 79 (79): 334-340, 2010

      23 Zhang L, "Dietary intake of PCDD/Fs and dioxin-like PCBs from the Chinese total diet study in 2007" 90 (90): 1625-1630, 2013

      24 Darnerud PO, "Dietary intake estimations of organohalogen contaminants(dioxins, PCB, PBDE and chlorinated pesticides, e. g. DDT)based on Swedish market basket data" 44 (44): 1597-1606, 2006

      25 De Mul A, "Dietary exposure to dioxins and dioxin-like PCBs in The Netherlands anno 2004" 51 (51): 278-287, 2008

      26 Bilau M, "Dietary exposure to dioxin-like compounds in three age groups : results from the Flemish environment and health study" 70 (70): 584-592, 2008

      27 Kim M, "Decreasing concentrations of PCDD/Fs in pork based on Korean monitoring in years 2002 and 2005" 25 (25): 1278-1282, 2008

      28 Bocio A, "Daily intake of polychlorinated dibenzop-dioxins/polychlorinated dibenzofurans(PCDD/PCDFs)in foodstuffs consumed in Tarragona, Spain : a review of recent studies(2001-2003)on human PCDD/PCDF exposure through the diet" 97 (97): 1-9, 2005

      29 Schwarz M, "Carcinogenic risks of dioxin : mechanistic considerations" 43 (43): 19-34, 2005

      30 EC, "COMMISSION REGULATION (EU) No 1259/2011 of 2 December 2011, amending Regulation (EC) No 1881/2006 as regards maximum levels for dioxins, dioxin-like PCBs and non dioxin-like PCBs in foodstuffs" L380 : 6-, 2011

      31 Kim M, "Background levels and dietary intake of PCDD/Fs in domestic and imported meat in South Korea" 69 (69): 479-484, 2007

      32 Arisawa K, "Background exposure to PCDDs/PCDFs/PCBs and its potential health effects : a review of epidemiologic studies" 52 (52): 10-21, 2005

      33 Fattore E, "Assessment of the dietary exposure to non-dioxin-like PCBs of the Italian general population" 73 (73): S278-S283, 2008

      34 Muntean N, "Assessment of dietary exposure to some persistent organic pollutants in the Republic of Karakalpakstan of Uzbekistan" 111 (111): 1306-1311, 2003

      35 Hsu MS, "A total diet study to estimate PCDD/Fs and dioxin-like PCBs intake from food in Taiwan" 67 (67): S65-S70, 2007

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