It is generally accepted that rotavirus infection (RVI) is limited to the mucosa of gastrointestinal tract (GIT), and the clinical outcome of infected babies is favorable. However, extraintestinal infections and invasive diseases associated with virem...
It is generally accepted that rotavirus infection (RVI) is limited to the mucosa of gastrointestinal tract (GIT), and the clinical outcome of infected babies is favorable. However, extraintestinal infections and invasive diseases associated with viremia can develop very occasionally. Clinical manifestations of RVI among neonates is believed to be milder than in infants and young children, but rarely some of babies suffer from severe illnesses of GIT. I report two cases of necrotizing enterocolitis associated with RVI in premature infants with a brief review of associated literatures.