The use of light‐activated triphenylphosphonium‐based antimicrobials to tackle the emerging problem of antimicrobial resistance has been proposed in this study. Chemical modification of phenalenone and perylene with triphenylphosphonium cations en...
The use of light‐activated triphenylphosphonium‐based antimicrobials to tackle the emerging problem of antimicrobial resistance has been proposed in this study. Chemical modification of phenalenone and perylene with triphenylphosphonium cations enhances their photoantimicrobial activity up to 107 times. Selective targeting of Gram‐positive bacteria is demonstrated.
Further details can be found in the article by Roger Bresolí‐Obach, Ignacio Gispert and Diego García Peña et al. (e201800054).
Cover art by M. Eugenio Vázquez, @ChemBioUSC
The use of light‐activated triphenylphosphonium‐based antimicrobials to tackle the emerging problem of antimicrobial resistance has been proposed in this study. Chemical modification of phenalenone and perylene with triphenylphosphonium cations enhances their photoantimicrobial activity up to 107 times. Selective targeting of Gram‐positive bacteria is demonstrated.
Further details can be found in the article by Roger Bresolí‐Obach, Ignacio Gispert and Diego García Peña et al. (e201800054).
Cover art by M. Eugenio Vázquez, @ChemBioUSC