Basic principles and applications of 18F-FDG-PET/CT in oral and maxillofacial imaging: A pictorial essay

다국어 초록 (Multilingual Abstract)

A combination of positron emission tomography (PET) with 18F-labeled fluoro-2-deoxyglucose (18F-FDG) and computed tomography (18F-FDG-PET/CT) has increasingly become a widely used imaging modality for the diagnosis and management of head and neck cancer. On the basis of both recent literature and our professional experience, we present a set of principles with pictorial illustrations and clinical applications of FDG-PET/CT in the evaluation and management planning of squamous cell carcinoma of the oral cavity and oropharynx. We feel that this paper will be of interest and will aid the learning of oral and maxillofacial radiology trainees and practitioners.

참고문헌 (Reference)

1 Antoch G, "Whole-body dual-modality PET/CT and whole-body MRI for tumor staging in oncology" 290 : 3199-3206, 2003

2 McHam SA, "Who merits a neck dissection after definitive chemoradiotherapy for N2-N3 squamous cell head and neck cancer?" 25 : 791-798, 2003

3 Porceddu SV, "Utility of positron emission tomography for the detection of disease in residual neck nodes after(chemo)radiotherapy in head and neck cancer" 27 : 175-181, 2005

4 Zimmer LA, "The use of combined PET/CT for localizing recurrent head and neck cancer : the Pittsburgh experience" 84 : 108-110, 2005

5 Ha PK, "The role of positron emission tomography and computed tomography fusion in the management of early-stage and advanced-stage primary head and neck squamous cell carcinoma" 132 : 12-16, 2006

6 Yao M, "The role of FDG PET in management of neck metastasis from head-and-neck cancer after definitive radiation treatment" 63 : 991-999, 2005

7 Layland MK, "The influence of lymph node metastasis in the treatment of squamous cell carcinoma of the oral cavity, oropharynx, larynx, and hypopharynx: N0versus N+" 115 : 629-639, 2005

8 Brouwer J, "Screening for distant metastases in patients with head and neck cancer: is there a role for (18)FDG-PET?" 42 : 275-280, 2006

9 de Visscher AV, "Routine long-term follow-up in patients treated with curative intent for squamous cell carcinoma of the larynx, pharynx, and oral cavity. Does it make sense?" 120 : 934-939, 1994

10 Torizuka T, "Prognostic value of 18F-FDG PET in patients with head and neck squamous cell cancer" 192 : W156-W160, 2009

11 Machtay M, "Pretreatment FDG-PET standardized uptake value as a prognostic factor for outcome in head and neck cancer" 31 : 195-201, 2009

12 Allal AS, "Prediction of outcome in head-and-neck cancer patients using the standardized uptake value of 2-[18F]fluoro-2-deoxy-D-glucose" 59 : 1295-1300, 2004

13 Yau YY, "Positron emission tomography/computed tomography true fusion imaging in clinical head and neck oncology : early experience" 63 : 479-486, 2005

14 Jones J, "Positron emission tomography(PET)in the management of oro-pharyngeal cancer" 31 : 170-176, 2005

15 Ryan WR, "Positron emission tomography for surveillance of head and neck cancer" 115 : 645-650, 2005

16 Chandra R, "Nuclear medicine physics: the basics" Lippincott Williams & Wilkins 2004

17 Suzuki H, "Limitations of FDG-PET and FDG-PET with computed tomography for detecting synchronous cancer in pharyngeal cancer" 134 : 1191-1195, 2008

18 Kubota R, "Intratumoral distribution of fluorine-18-fluorodeoxyglucose in vivo : high accumulation in macrophages and granulation tissues studied by microautoradiography" 33 : 1972-1980, 1992

19 Goerres GW, "Impact of whole body positron emission tomography on initial staging and therapy in patients with squamous cell carcinoma of the oral cavity" 39 : 547-551, 2003

20 Branstetter BF 4th, "Head and neck malignancy:Is PET/CT more accurate than PET or CT alone?" 235 : 580-586, 2005

21 Forastiere A, "Head and neck cancer" 345 : 1890-1900, 2001

22 Krabbe CA, "FDG PET in oral and oropharyngeal cancer. Value for confirmation of N0 neck and detection of occult metastases" 44 : 31-36, 2008

23 Freudenberg LS, "Dual modality of 18F-fluorodeoxyglucose-positron emission tomography/computed tomography in patients with cervical carcinoma of unknown primary" 14 : 155-160, 2005

24 Blodgett TM, "Combined PET-CT in the head and neck: part 1. Physiologic, altered physiologic, and artifactual FDG uptake" 25 : 897-912, 2005

25 Fukui MB, "Combined PET-CT in the head and neck. Part 2. Diagnostic uses and pitfalls of oncologic imaging" 25 : 913-930, 2005

26 Kwee TC, "Combined FDG-PET/CT for the detection of unknown primary tumors : systematic review and metaanalysis" 19 : 731-744, 2009

27 Jemal A, "Cancer statistics, 2006" 56 : 106-130, 2006

28 Veeramachaneni R, "Benign myoepithelioma of the lung : a case report and review of the literature" 125 : 1494-1496, 2001

29 Kim MR, "18Ffluorodeoxyglucose-positron emission tomography and bone scintigraphy for detecting bone metastases in patients with malignancies of the upper aerodigestive tract" 44 : 148-152, 2008

30 Ng SH, "18F-FDG PET and CT/MRI in oral cavity squamous cell carcinoma:a prospective study of 124 patients with histologic correlation" 46 : 1136-1143, 2005