간질성 폐질환의 영상의학적 소견 = Radiologic Diagnosis of Interstitial Lung Diseases

다국어 초록 (Multilingual Abstract)

Diffuse interstitial lung diseases (DILD) are a group of chronic disorders showing varying

degrees of active inflammation and established fibrosis mainly involving the interstitium of

the lungs. DILD can be classified into two groups in an etiologic aspect; idiopathic and DILD with

known-cause, such as connective tissue diseases associated with DILD. Although there had

been complexity and variability in the classification of idiopathic interstitial pneumonia (IIP), an

international standard was established for the classification of IIPs including seven clinicalradiologic-

pathologic entities; idiopathic pulmonary fibrosis (IPF), nonspecific interstitial pneumonia

(NSIP), cryptogenic organizing pneumonia (COP), acute interstitial pneumonia (AIP),

respiratory bronchiolitis-associated interstitial lung disease (RB-ILD), desquamative interstitial

pneumonia (DIP), and lymphoid interstitial pneumonia (LIP). The prognosis of fibrotic NSIP and

IPF is much poorer compared to those of other spectrum of IIPs, such as COP, RB-ILD, DIP,

and LIP. Therefore, fibrotic NSIP and IPF can be considered separately as a group of fibrotic

IIPs. Trying to predict the prognosis of IIPs, there has been an effort to differentiate inflammationpredominant

lesions from fibrosis-predominant lesions in patients with fibrotic IIPs. Radiologic

features of low fibrotic scores at high-resolution CT and early enhancement patterns at dynamic

enhancement of MRI can be useful prognostic determinants for the prediction of disease

improvement in patients with fibrotic IIPs.

참고문헌 (Reference)

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