P172 : Clinicohistopathologic patterns of extra mammary Paget`s disease = P172 : Clinicohistopathologic patterns of extra mammary Paget`s disease

다국어 초록 (Multilingual Abstract)

Background: Though the histology of extra mammary Paget`s disease(EMPD) is known to be variable pattern; it has not been studied in Korean patients. Objectives: The purpose of this study is to investigate clinicohistopathologic patterns of EMPD. We also tried to find out any histologic findings that can influence its clinical behavior. Methods: We reviewed the medical records and the skin biopsy slides of 11 patients with EMPD. Clinical information for each patient included sex, age, duration of the disease, location, underlying malignancy. Results: There were 8 males and 3 females(Mean age, 65.5 years old). Mean duration of the disease was 17.4 months. The tumor cell proliferation pattern showed: single cell pattern, 69.2%; nest pattern, 69.2%; acantholysis-like pattern, 53.8%; glandular pattern, 15.4%. Combined pattern (more than two patterns) was shown in 69.2%. There were 9 in situe EMPD and 4 invasive EMPD. Conclusion: Korean patients showed various types of histology of EMPD. Not only single cell pattern, also nest and acantholysis-like patterns are common. Most of the cases showed combined pattern. Its relationship with clinical behavior was not revealed.