폐쇄성 수면무호흡증 리스크와 혈중 지질 수치와의 연관성 = Association between the Risk of Obstructive Sleep Apnea and Blood Lipid Levels

다국어 초록 (Multilingual Abstract)

Background: Obstructive sleep apnea (OSA) increases the risk of dyslipidemia, thereby heightening the likelihood of developing cardiovascular diseases. Hence, prior to the diagnosis of OSA, it is essential to investigate the association with dyslipidemia in at-risk individuals.
Methods: Using raw data obtained from the 2021 Korea National Health and Nutrition Examination Survey, we examined the details of 2,882 participants aged 40 years and older, who were not diagnosed with sleep apnea and did not use lipid-lowering medications. Participants who had reported snoring, fatigue, or witnessed apnea episodes, were categorized into the “OSA Risk Group” (OSARG), and logistic regression analysis was performed to examine the association between serum lipid levels and dyslipidemia.
Results: OSARG participants were found to have a higher prevalence of hypertriglyceridemia and increased prevalence of dyslipidemia. After adjusting for sex, age, education, economic status, housing type, obesity, physical activity, smoking, and alcohol consumption, only hypertriglyceridemia remained significantly associated with the OSARG, and the odds ratio for OSA was significantly higher among those patients with hypertriglyceridemia (1.39; 95% confidence interval, 1.06–1.83).
Conclusion: Among adults aged 40 years and older, compared with those not at risk, individuals at risk of OSA were characterized by a higher prevalence of hypertriglyceridemia. These findings thus indicate that the management of hypertriglyceridemia and dyslipidemia may be warranted prior to the diagnosis of OSA in this population.