NMR Assignment and Antimicrobial/Antioxidant Activities of 1β-Hydroxyeuscaphic acid from the Seeds of Butyrospermum parkii

다국어 초록 (Multilingual Abstract)

Phytochemical investigation of the EtOAc and n-BuOH fractions obtained from the crude methanol
extract of the seeds of Butyrospermum parkii led to the isolation of seven compounds including 1β,2α,3α-
trihydroxyurs-12-en-28-oic acid (1β-hydroxyeuscaphic acid) which full NMR assignment is herein reported for
the first time. The above extract, fractions and some of the isolated compounds were screened for antimicrobial
and antioxidant activities; 1β-hydroxyeuscaphic acid was the more potent.

참고문헌 (Reference)

1 Hirai, N., "Triterpene phytoalexins from strawberry fruit" 64 : 1707-1712, 2000

2 Mats, H., "Trihydroxyoctadecenoic acids in beers: qualitative and quantitative analysis" 39 : 1568-1572, 1991

3 Teponno, R.B., "Three new clerodane diterpenoids from the bubils of Dioscorea bulbifera var. sativa" 90 : 1599-, 2007

4 Hall, C.A., "Structure activities of natural antioxidants. In Antioxidant Methodology In Vitro Concepts" Elsevier Applied Science 1-18, 1997

5 Tapondjou, A.L, "Sphingolipids and other constituents from Cordia platythyrsa" 33 : 1293-1297, 2005b

6 Mensor, L.L., "Screening of Brazilian plant extracts for antioxidant activity by the use of DPPH free radical method" 15 : 127-130, 2001

7 Lavaud, C., "Saponins from three species of Mimusops" 41 : 887-893, 1996

8 Seto, R., "Preparation of epimers of tea catechins by heat treatment" 61 : 1434-1439, 1997

9 Ponou, K.B., "Polyhydroxyoleananetype triterpenoids from Combretum molle and their anti- inflammatory activity" 1 : 183-187, 2008

10 Ogunwande, I.A., "Phytochemical and antimicrobial studies on Butyrospermum paradoxum" 72 : 54-56, 2001

11 Wandji, J., "Pentacyclic triterpenoid and saponins from Gambeya boukokoensis" 64 : 845-849, 2003

12 Guang-Yi, L., "Pentacyclic triterpenes from the fruits of Rosa sterilis" 52 : 162-166, 1999

13 Pawar, R.S., "Effect of oleanane triterpenoids from Terminalia arjuna, a cardioprotective drug on the process of respiratory oxyburst" 12 : 391-393, 2005

14 Garcez, R.F., "Bioactive flavonoids and triterpenes from Terminalia fagifolia (Combretaceae)" 17 : 1223-1228, 2006

15 Tapondjou, A.L., "Bancoensone, A new antioxidant caffeoyl derivative from Cussonia bancoensis" 1 : 57-61, 2005a

16 Teponno, R.B., "Bafoudiosbulbins A and B, two antisalmonellal clerodane diterpenoids from Dioscorea bulbifera var. sativa" 67 : 1957-1963, 2006

17 Carbonnelle, B., "Bacteriologie médicale: Techniques usuelles" SIMEP 1987

18 Kuete, V., "Antitumor, antioxidant and antimicrobial activities of Bersama engleriana (Melianthaceae)" 115 : 494-501, 2008

19 Montilla, M.P., "Antioxydant activity of maslinic acid, a triterpene derivative obtained from Olea europea" 69 : 472-474, 2003

20 Pietta, P., "Antioxidant activity of selected medicinal plants" 46 : 4487-4490, 1998

21 Mims, C.A., "Antimicrobials and chemotherapy" Med. Microbiol. Rev 1-34, 1993

22 Djoukeng, J.D., "Antibacterial triterpenes from Syzygium guineense(Myrtaceae)" 101 : 283-286, 2005

23 Yamauchi, R., "Analysis of molecular species of Glycolipids in fruit pastes of red bell pepper(Capsicum annum L.) by HPLC-MS" 49 : 622-627, 2001

24 Kapseu, C., "Acides gras et triglycérides du beurre de karité du Cameroun" 58 : 31-34, 2001

25 Barre, J.T., "A bioactive triterpene from Lantana camara" 45 : 321-324, 1997

26 Chang, Y.C., "(E) N-(4- hydroxyphenethyl)-4-hydroxycinnamamide" 48 : 811-816, 2001