2002년 2월부터 2005년 4월까지 호흡기질환 환자로부터 분리된 M. pneumeniae 123 균주의 tetracycline과 erythromycin에 대한 MIC 범위는 각각 $0.5\~1.0$, and $0.5\~512{\mu}/ml$ 이었다. 분리된 M. pneumoniae 123 균주에...
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https://www.riss.kr/link?id=A103757705
장명웅 (고신대학교) ; 박인달 (고신대학교) ; 김광혁 (고신대학교) ; 송갑영 (부산 위생병원) ; 김성원 (부산 성분도병원) ; Chang Myung-Woong ; Park In-Dal ; Kim Kwang-Hyuk ; Song Gap-Young ; Kim Sung-Won
2005
Korean
KCI등재
학술저널
863-870(8쪽)
2
0
상세조회0
다운로드국문 초록 (Abstract)
2002년 2월부터 2005년 4월까지 호흡기질환 환자로부터 분리된 M. pneumeniae 123 균주의 tetracycline과 erythromycin에 대한 MIC 범위는 각각 $0.5\~1.0$, and $0.5\~512{\mu}/ml$ 이었다. 분리된 M. pneumoniae 123 균주에...
2002년 2월부터 2005년 4월까지 호흡기질환 환자로부터 분리된 M. pneumeniae 123 균주의 tetracycline과 erythromycin에 대한 MIC 범위는 각각 $0.5\~1.0$, and $0.5\~512{\mu}/ml$ 이었다. 분리된 M. pneumoniae 123 균주에서 plasmid DNA는 확인되지 않았다. 분리된 M. pneumoniae 123 균주 중에서 57($46.3\%$) 균주가 tetracycline에 저항성인 tetM유전자를 가지고 있었으며, 235 rRNA domain V에 erythromycin에 저항성 변이를 일으킨 균주가 60($48.8\%$)이었다. erythromycin에 저항성 변이를 일으키지 않은 63균주 중에서 tetM 유전자를 가지고 있는 균주는 36($57.1\%$)이었으며, erythromycin에 저항성 변이를 일으킨 60균주 중에서 21($35.0\%$ 균주가 tetM 유전자를 가지고 있었다. 본 연구로써 국내에서 tetracycline과 erythromycin에 대한 저항성 M. pneumoniae 균주의 분리율이 외국에 비하여 높으며, M. pneumoniae 감염의 치료에 erythromycin이 일차 선택제가 될 수 없으므로 이에 대한 범국가적 조사가 필요하다고 생각된다.
다국어 초록 (Multilingual Abstract)
One hundred and twenty three strains of Mycoplasma pneumoniae were isolated from patients with respiratory diseases from February 2002 to April 2005 in Busan, Korea. The MICs of tetracycline and erythromycin up to $90\%$ of the 123 M. pneumoniae isola...
One hundred and twenty three strains of Mycoplasma pneumoniae were isolated from patients with respiratory diseases from February 2002 to April 2005 in Busan, Korea. The MICs of tetracycline and erythromycin up to $90\%$ of the 123 M. pneumoniae isolates tested were $0.5\~1.0$, and $0.5\~512{\mu}/ml$, respectively. Plasmid DNA was not isolated from all of the M. pneumoniae isolates. Out of 323 strains of M. pneumoniae, 57 ($46.3\%$) stains contain tetM gene on their chromosomal DNA, and 60 ($48.8\%$) strains were mutated in domain V of 23S rRNA for erythromycin resistance. Out of 63 strains of M. pneumoniae which were not mutated in domain V of 235 rRNA for erythromycin resistance, 36 ($57.1\%$) strains contained tetM gene, and out of 60 strains of M. pneumoniae which were mutated in domain V of 23S rRNA for erythromycin resistance, 21 ($35.0\%$) strains contained tetM gene. These results suggest that the isolation rate of erythromycin and tetracycline resistant M. pneumoniae is higher than those of other countries, and erythromycin and tetracycline are not first choice drug for M. pneumoniae infection in Korea, and it need confirm by a nationwide surveilance of antimicrobial resistance.
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매생이 추출물이 난소를 절제한 흰쥐의 혈소판 응집과 혈청 내 지질 조성에 미치는 영향
오디가 난소를 절제한 흰쥐 결함조직 중의 collagen 함량 변화에 미치는 영향
Bacillus subtilis BK-17 유래 혈전용해 효소의 특성
학술지 이력
연월일 | 이력구분 | 이력상세 | 등재구분 |
---|---|---|---|
2027 | 평가예정 | 재인증평가 신청대상 (재인증) | |
2021-01-01 | 평가 | 등재학술지 유지 (재인증) | |
2018-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2015-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2011-08-03 | 학술지명변경 | 외국어명 : Korean Journal of Life Science -> Journal of Life Science | |
2011-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2009-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2007-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2004-01-01 | 평가 | 등재학술지 선정 (등재후보2차) | |
2003-01-01 | 평가 | 등재후보 1차 PASS (등재후보1차) | |
2001-07-01 | 평가 | 등재후보학술지 선정 (신규평가) |
학술지 인용정보
기준연도 | WOS-KCI 통합IF(2년) | KCIF(2년) | KCIF(3년) |
---|---|---|---|
2016 | 0.37 | 0.37 | 0.42 |
KCIF(4년) | KCIF(5년) | 중심성지수(3년) | 즉시성지수 |
0.43 | 0.43 | 0.774 | 0.09 |