Baseline heart rate variability in children and adolescents with vasovagal syncope

다국어 초록 (Multilingual Abstract)

Purpose: This study aimed to evaluate the autonomic imbalance in syncope by comparing the baselineheart rate variability (HRV) between healthy children and those with vasovagal syncope.
Methods: To characterize the autonomic profile in children experiencing vasovagal syncope, weevaluated the HRV of 23 patients aged 7–18 years and 20 healthy children. These children weredivided into preadolescent (<12 years) and adolescent groups. The following time-domain indices werecalculated: root mean square of the successive differences (RMSSD); standard deviation of all averageR-R intervals (SDNN); and frequency domain indices including high frequency (HF), low frequency (LF),normalized high frequency, normalized low frequency, and low frequency to high frequency ratio (LF/HF).
Results: HRV values were significantly different between healthy children and those with syncope.
Student t test indicated significantly higher SNDD values (60.46 ms vs. 37.42 ms, P =0.003) andRMSSD (57.90 ms vs. 26.92 ms, P=0.000) in the patient group than in the control group. In thepatient group, RMSSD (80.41 ms vs. 45.89 ms, P =0.015) and normalized HF (61.18 ms vs. 43.19ms, P =0.022) were significantly higher in adolescents, whereas normalized LF (38.81 ms vs. 56.76ms, P =0.022) and LF/HF ratio (0.76 vs. 1.89, P =0.041) were significantly lower in adolescents. Incontrast, the control group did not have significant differences in HRV values between adolescents andpreadolescents.
Conclusion: The results of this study indicated that children with syncope had a decreased sympathetictone and increased vagal tone compared to healthy children. Additionally, more severeautonomic imbalances possibly occur in adolescents than in preadolescents.

참고문헌 (Reference)

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