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      폐쇄성 수면 무호흡증 환자에서 동반된 불면증상이 성별에 따라 우울, 불안, 피로, 주간졸음증에 미치는 영향 = Gender differences in the effect of comorbid insomnia symptom on depression, anxiety, fatigue, and daytime sleepiness in patients with obstructive sleep apnea

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      https://www.riss.kr/link?id=T13098533

      • 저자
      • 발행사항

        울산 : 울산대학교 대학원, 2013

      • 학위논문사항

        학위논문(석사) -- 울산대학교 대학원 , 의학과 , 2013. 2

      • 발행연도

        2013

      • 작성언어

        영어

      • 발행국(도시)

        울산

      • 형태사항

        iii, 19 p. : 삽화 ; 30 cm

      • 일반주기명

        울산대학교 논문은 저작권에 의해 보호받습니다.
        지도교수: 이상암
        참고문헌 : p.16-18

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        • 울산대학교 도서관 소장기관정보
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      다국어 초록 (Multilingual Abstract)

      This study investigated gender differences in the effect of comorbid insomnia symptom on depression, anxiety, fatigue, daytime sleepiness, and quality of life (QOL) in patients with obstructive sleep apnea (OSA). There are gender differences in the presentation of OSA. However, the influence of gender on the presentation of comorbid insomnia symptom and OSA is not known. All participants performed overnight polysomnography in single university hospital sleep laboratory and completed a battery of questionnaires including Beck Depression Inventory, State-Trait Anxiety Inventory, Multidimensional Fatigue Inventory, Epworth Sleepiness Scale, and Short Form-36 Health Survey. Insomnia symptom was defined as present if a patient had any insomnia complaints longer than one month and at least one time per week. 655 adult patients with OSA were enrolled in this study. Among them, 233 (35.5%) reported comorbid insomnia symptom with OSA, which was not more prevalent in women than in men. The severity of OSA was not related to comorbid insomnia symptom. Based on linear regression, women had higher depression, fatigue, and daytime sleepiness and lower health-related QOL than men (all, p<0.05). The presence of insomnia symptom had negative effects on fatigue (p=0.005) and QOL only (p=0.015) in men but not in women when taking gender-by-insomnia interaction into consideration. There were significant differences in PSG-based sleep architecture between the OSA-only and OSA-insomnia groups, but only in the subgroup of men. In conclusion, men are more prone to the negative impact of comorbid insomnia symptom and OSA on their level of fatigue and QOL than women.
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      This study investigated gender differences in the effect of comorbid insomnia symptom on depression, anxiety, fatigue, daytime sleepiness, and quality of life (QOL) in patients with obstructive sleep apnea (OSA). There are gender differences in the pr...

      This study investigated gender differences in the effect of comorbid insomnia symptom on depression, anxiety, fatigue, daytime sleepiness, and quality of life (QOL) in patients with obstructive sleep apnea (OSA). There are gender differences in the presentation of OSA. However, the influence of gender on the presentation of comorbid insomnia symptom and OSA is not known. All participants performed overnight polysomnography in single university hospital sleep laboratory and completed a battery of questionnaires including Beck Depression Inventory, State-Trait Anxiety Inventory, Multidimensional Fatigue Inventory, Epworth Sleepiness Scale, and Short Form-36 Health Survey. Insomnia symptom was defined as present if a patient had any insomnia complaints longer than one month and at least one time per week. 655 adult patients with OSA were enrolled in this study. Among them, 233 (35.5%) reported comorbid insomnia symptom with OSA, which was not more prevalent in women than in men. The severity of OSA was not related to comorbid insomnia symptom. Based on linear regression, women had higher depression, fatigue, and daytime sleepiness and lower health-related QOL than men (all, p<0.05). The presence of insomnia symptom had negative effects on fatigue (p=0.005) and QOL only (p=0.015) in men but not in women when taking gender-by-insomnia interaction into consideration. There were significant differences in PSG-based sleep architecture between the OSA-only and OSA-insomnia groups, but only in the subgroup of men. In conclusion, men are more prone to the negative impact of comorbid insomnia symptom and OSA on their level of fatigue and QOL than women.

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      목차 (Table of Contents)

      • Abstract i
      • 표 차례 iii
      • Background 1
      • Patients and Methods 2
      • Results 5
      • Abstract i
      • 표 차례 iii
      • Background 1
      • Patients and Methods 2
      • Results 5
      • Discussion 13
      • Conclusion 15
      • References 16
      • 국문요약 19
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