Study for Usefulness and Safety of Sonography-Guided High-Intensity Focused Ultrasound Ablation of Uterine Myoma = Study for Usefulness and Safety of Sonography-Guided High-Intensity Focused Ultrasound Ablation of Uterine Myoma

국문 초록 (Abstract)

목적: The Objective of this study is to evaluate the usefulness and safety of US-guided high-intensity focused ultrasound(HIFU) ablation of uterine myoma. 방법: 78 patients with symptomatic uterine myoma underwent US-guided HIFU ablation with Model JC Focused Ultrasound Tumor Therapeutic System, Chongqing Haifu (HIFU) Technology Co. between April 2013 and October 2013 in St. Peter`s Hospital, Seoul, Korea.The study group designed by 27 patients who were followed up for 6 months after treatment. We assessed the differences volume at baseline and 6 months after treatment. Volume of myomas was checked using contrast-enhanced T1-weighted image on MRI. Also we evaluated safety of HIFU by presence of complications. Myomas were ablated using HIFU with a power output of 410W. The treatment time was different according to size of uterine myoma and type of myoma from 325 sec to 2534 sec. Follow up MRI scan were done 6 months after treatment. 결과: Mean age age of patients was 40.11 +/- 6.22 (29-51) years. Location of myomas targeted were intramural type 23 cases, anterior 12 csaes, posterior 5 cases, lateral 3 cases, fundus 3 cases, submucosal type 3 cases, subserosal type 1 case. We divided 3 groups, below 100 cm3, 100-200 cm3, above 200 cm3 on volume of myoma at baseline(cm3). Mean volume of contrast-enhanced T1-weighted image on MRI was 225.55(35.81-834.43) cm3 before HIFU treatment and 84.64(9.19-343.90) cm3 6 months after HIFU treatment. Reduction rate was 62.47(%)t. No severe complications like bowel injury, bladder injury, infection was not observed. 결론: US-guided HIFU treatment can be a safe and useful to ablate uterine myoma.