Schwannoma is a benign, solitary, slow-growing tumor of the nerve sheath, arising most commonly in the head, neck, upper and lower extremities, posterior mediastinum and retroperitoneum. It rarely affects the female genital system, with less than 10 c...
Schwannoma is a benign, solitary, slow-growing tumor of the nerve sheath, arising most commonly in the head, neck, upper and lower extremities, posterior mediastinum and retroperitoneum. It rarely affects the female genital system, with less than 10 cases reported involving vulvar. We report a 37-year-old woman with a 3 cm sized painless tumor of the vulva. The tumor, located under the dermis and encapsulated, was excised for treatment and biopsy. A histological examination revealed spindle-shaped cells with ovoid or elongated nuclei. Also, a swirling pattern with some palisading pattern of nuclei in H.E. stains. Immunohistochemical studies showed the tumor to be positive for S-100 protein, findings compatible with diagnosis of Schwannoma.