The association between benign symmetric lipomatosis and heavy alcohol intake = The association between benign symmetric lipomatosis and heavy alcohol intake

다국어 초록 (Multilingual Abstract)

Background: Benign symmetric lipomatosis (BSL) is rare disorder characterized by painless, enlarging, diffuse, and symmetric deposits of subcutaneous fat predominantly around the neck, shoulders, and upper extremities. Objectives: The purpose of this study is to analyse the clinical and laboratory features of BSL and its association with alcoholism. Methods: Sixteen patients, histologically diagnosed as BSL, were included in this study. We assessed alcohol intake to evaluate whether patient is high risk drinker ( ? 7 drinks of alcohol for male and ? 5 drinks of alcohol for female on a single day at least 2 times a week) and laboratory findings of them. Results: The patients were between 28 and 63 years of age with mean age of 46 years. Thirteen of the 16 patients were male, and 3 were female. The common sites of occurrence were the arm, leg, and abdomen. Five of 16 patients were presented with tender nodules. Seven patients (43.8%) were high risk drinker and 5 patients (31.3%) were non-drinker. Percentage of high risk drinker among BSL included in this study was higher than that among Korean adult (11.9%). In laboratory findings, abnormal values in liver function tests were observed in 7 patients (43.8%) and hyperlipidemia was observed in 6 patients (37.5%). Conclusion: Benign symmetric lipomatosis is frequently associated with heavy alcohol intake, abnormal liver function and hyperlipidemia.