사람 적혈구에 있어서 극성 대사물질과 막 구성분의 Uptake 에 관한 1 - Palmitoyllysolecithin 과 인산 Saponin 의 영향 = The Effect of 1 - Palmitoyllysolecithin and Ginseng Saponin on the Uptake of Polar Metabolites and membrane Components to Human Erythrocytes

다국어 초록 (Multilingual Abstract)

The effects of Lysolecithin and ginseng saponin on the uptake of [^(14)C]-alanine, [^(14)C]-glucose, [^(14)C]-cholesterol, and [^(14)C]-phosphatidylethanolamine to human erythrocytes in the various conditions were as follows. When the human erythrocytes pretreated in the presence of low lytic amount of lysolecithin, the uptake of such polar metabolites and membrane components was enhanced up to [^(14)C]-alanine 111%, [^(14)C]-glucose 43%, [^(14)C]-cholesterol 48%, and [^(14)C]-phosphatidylethanolamine 17%, In case of saponin pretreatment, the uptakes of such substances were increased to 408%, 70%, 28%, and 10%, respectively. In comparison with both lytic surfactants under the optimum concentration, lysolecithin was more effective to the uptake of membrane components, cholesterol and phosphatidylethanolamine. On the other hand, saponin was more potent to the polar metabolite uptake into the erythrocytes.