Trifluoromethylated 3‐(Pyrazol‐1‐yl)propanamide (PPA) Ligands

다국어 초록 (Multilingual Abstract)

The new PPA ligands 3‐[5‐methyl‐3‐(trifluoromethyl)‐1H‐pyrazol‐1‐yl]propanamide (CF3MePPA; 3) and 3‐[3,5‐bis(trifluoromethyl)‐1H‐pyrazol‐1‐yl]propanamide ((CF3)2PPA; 4) were synthesized by Aza‐Michael addition of the specific pyrazole derivatives to acrylamide. Both products were characterized by elemental analyses, IR and NMR spectroscopy, and mass spectrometry. X‐Ray structure determination of 3 revealed the presence of a one‐dimensional hydrogen‐bonded structure in the solid state. The ligating ability of the new ligands towards PdCl2 was studied, showing that 3 behaves similar to Me2PPA and reacts cleanly with PdCl2 to afford the sparingly soluble complex PdCl2(CF3MePPA‐κN)2. By contrast, the donor ability of pyrazolyl group in 4 was found to be considerably reduced, thus resulting in the formation of the unusual complex PdCl2{(CF3)2PPA‐κN}{(CF3)2PPA‐κO}.