The objective of this study is to observe and compare the morphology of female genital
organs such as ovary and oviduct in premature and mature rats. Female Sprague-Dawley rats
were divided into two groups; premature(2 weeks of age) and mature(8 weeks...
The objective of this study is to observe and compare the morphology of female genital
organs such as ovary and oviduct in premature and mature rats. Female Sprague-Dawley rats
were divided into two groups; premature(2 weeks of age) and mature(8 weeks of age). Rats were
anesthetized with ethyl ether and female genital organs were removed. Light microscope
specimens were prepared by routine method: fixed in 10% formalin, embedded in paraffin block,
cut with a microtome, and stained by hematoxylin and eosin. In the case of premature rats, there
were primitive, primary and growing follicles, but not any corpus luteum in the ovary. And
oviduct showed the simple structure composing less developed mucosa, submucosa, muscle and
serosa. In the case of mature rats, however, various stages of developing follicles and corpus
luteum could be seen in the ovary. Particularly, Graafian follicles at the periphery and corpus
luteum at the medulla were present in the same time. Mature oviduct was characterized by folded
villi, thick mucosa and plentiful blood vessels. On conclusion, structural and functional
differentiation of female genital organs such as ovary and oviduct is correlated with gonadotropins
at puberty.