Differences of Photographs Inducing Craving Between Alcoholics and Non-alcoholics

다국어 초록 (Multilingual Abstract)

Many researchers have used cue reactivity paradigm to study alcohol craving. But the difference of craving response to drinks between alcoholic patients and social drinkers was little evaluated. To investigate characteristics of alcohol-related visual cues which induce alcohol craving in alcoholism, we examined the response of subjects to alcohol-related cues considering qualitative aspects. The authors developed 27 photographs related to alcohol as candidate visual cues. Thirty five patients with alcohol dependence, 35 heavy drinkers and 35 social drinkers were shown these pictures and asked to rate these 6 pictures in order of inducing alcohol craving the most. ‘A glass of Soju' and ‘A Party scene' were chosen as the alcohol-related visual cues which induced craving the most in the patients and heavy drinkers, respectively. The results suggest that the patients with alcohol dependence are more absorbed by alcohol without drinking context such as an atmosphere or situation involving drinking. Heavy drinkers may experience craving in anticipation of being in a drinking situation.

참고문헌 (Reference)

1 "provisional description of a clinical syndrome" 1058-61, bmj1976

2 "What is craving? Models and implications for treatment" 23 : 165-173, 1999

3 "The physicians' guide to helping patients with alcohol problems" Department of Health and Human Services 1995

4 "The influence of alcohol expectancy priming and mood manipulation on subsequent alcohol consumption" 109 : 106-115, 2000

5 "The effects of alcohol cues and an alcohol priming dose on a multi-factorial measure of subjective cue reactivity in social drinkers" 145 : 452-454, 1999

6 "The craving for alcohol" 35-8, qjstudalcohol1955

7 "Subcortical correlates of craving in recently abstinent alcoholic patients" 158 : 1075-1083, 2001

8 "Research perspectives on alcohol craving: an overview" 95 : 45-52, 2000

9 "Neural response to alcohol stimuli in adolescents with alcohol use disorder" 60 : 727-735, 2003

10 "Meta-analysis of cue-reactivity in addiction research" 94 : 327-340, 1999

11 "Measuring alcohol expectancies with the implicit-association test" 17 : 126-133, 2003

12 "Limbic activation during cue- induced cocaine craving" 156 : 11-18, 1999

13 "Implicit and explicit alcohol-related cognitions in heavy and light drinkers" 111 : 648-658, 2002

14 "Focal cerebral blood flow change during craving for alcohol measured by SPECT" 7 : 15-22, 1995

15 "Event-related potentials and cue-reactivity in alcoholism" 24 : 1724-1729, 2000

16 "Diagnostic and statistical manual of mental disorders" American Psychiatric Press 1994

17 "Development of alcohol-associated cues and cue-induced brain activation in alcoholics" 17 : 287-291, 2002

18 "Craving and relapse to drink" 108-30, qjstudalcohol1974

19 "Cognitive factors in the relapse process" Guilford Press 128-200, 1985

20 "Clinical characteristics and gene polymorphisms of aldehyde dehydrogenase II and arylsulfatase A in hospitalized patients with alcohol dependence" 4 : 93-101, 2000

21 "Challenges in the manipulation, assessment and interpretation of craving relevant variables" 95 : 177-187, 2000

22 "Addictive behavior: cue exposure theory and practice" John Wiley & Sons 1995

23 "Activation of prefrontal cortex and anterior thalamus in alcoholic subjects on exposure to alcohol-specific cues" 58 : 345-352, 2001