The reaction in tetrahydrofuran of potassium 9-(2,3-dimethyl-2-butoxy)-9-boratabicyclo [3. 3. 1]nonane (K 9-OThx-9-BBNH) with lithium chloride was examined in detail to establish the generality of this synthesis of the corresponding lithium derivative...
The reaction in tetrahydrofuran of potassium 9-(2,3-dimethyl-2-butoxy)-9-boratabicyclo [3. 3. 1]nonane (K 9-OThx-9-BBNH) with lithium chloride was examined in detail to establish the generality of this synthesis of the corresponding lithium derivatives. This new reagent, Li 9-OThx-9-BBNH, shows an excellent stereoselectivity .in the reduction of cyclic ketones. Especially, the easy removal of the byproduct of the reaction and thus simple isolation procedure provides a major advantage for this reagent.