Triterpensaponine und wertere Inhaltsstoffe aus der chinesische Droge Caulis Sargentodaxae(Sargentodoxae cuneate(oliv.) Rehd. et cils, Sargentodoxae)

국문 초록 (Abstract)

중국산 한약재 Sargentodoxae cuneata의 줄기(Stengel)부위를 petrolether/ether로 추출하고, 여기서 β-sitosteroldmd 분리하고, 메탄놀로 추출하였다. 이 메탄놀 추출물을 산 가수분해하여 compound I(2α, 3β-dihydroxy-ursa-12, 18-dien-17-carbonsaere), II(2α, 3α-dihydroxy-ursa-12, 18-dien-17-carbonsaere)를 분리하였다. 산 가수분해물을 다시 methylation하여 compound KM-1(2α, 3α, 19α-trihydroxy-ursa-12, 18-dien-17-carbonsaeremethylester), KM-II(2α-hydroxyursolsaueremethylester + 2α-hydroxyoleanolsaueremethylester), KM-IV(2α, 3β, 19α-trihydroxy-ursa-12, 18-dien-17-carbonsaeremethylester), KM-V(2α, 3α, 19α, 23α-tetrahydroxy-ursa-12, 18-dien-17-carbonsaeremethylester), M-1(2α, 3β-dihydroxy-ursa-12, 18-dien-17-carbonsaeremethylester)를 분리하였다. 메탄올 추출물을 ether, ethylacetate, n-Buthanol로 계통분리하였다. 이중에서 ethylacetate분획을 DCCC를 사용하여 compound S-I(2α, 3α, 19α-trihydroxy-ursa-12, 18-dien-17-carbonsaere-1-β-D-glucopyranosylester), S-II((2α,!
3!
β, 19α-trihydroxy-ursa-12, 18-dien-17-carbonsaere-1-β-D-glucopyranosylester)를 분리하였고, normal SiO₂ CC를 사용하여 compound A-I(+ catechin)를 분리하였다. compound I(2α, 3β-dihydroxy-ursa-12, 18-dien-17-carbonsaere), II(2α, 3α-dihydroxy-ursa-12, 18-dien-17-carbonsaere)는 산가수분해산물로써 처음으로 분리되어 구조분석되었다. M-1(2α, 3β-dihydroxy-ursa-12, 18-dien-17-carbonsaeremethylester)은 가수분해후 메틸화한 것으로 처음으로 분리되어 보고하였다.
compound S-I(2α, 3α, 19α-trihydroxy-ursa-12, 18-dien-17-carbonsaere-1-β-D-glucopyranosylester), S-II((2α, 3β, 19α-trihydroxy-ursa-12, 18-dien-17-carbonsaere-1-β-D-glucopyranosylester)은 hemolysis효능과 antiviral effect가 있음이 밝혀졌다.

다국어 초록 (Multilingual Abstract)

This paper identifies the characteristics of travel behavior for use in market segmentation. For the purpose od this study,four hypothetical travel characteristics were tested using logit analysis and survey data on air travel. The results indicated that the travel characteristics such as trip, mode consumer and travel characteristics were observed as important influetial factors in choosing a certain type of air travel.