LD_(50) of ouabain on the male and female mice pretreated with testosterone and susceptibility of ouabain on the excised auricular contractility of the male and female rabbits pretreated with testosterone were investigated.
The results obtained were ...
LD_(50) of ouabain on the male and female mice pretreated with testosterone and susceptibility of ouabain on the excised auricular contractility of the male and female rabbits pretreated with testosterone were investigated.
The results obtained were summarized as follows:
1. The LD_(50) of ouabain on the mouse pretreated with testosterone was increased in the both sex especially in female.
2. Effect of ouabain on the excised auricular contractility of rabbit pretreated with testosterone was increased in both sex and it was more marked in male than in female.