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      폐쇄성 수면무호흡증후군의 치료를 위한 구개수구개피판술 후 주간졸음 호전을 예측하기 위한 술전 인자 분석 = Prognostic Factors for Improved Daytime Sleepiness after Uvulopalatal Flap for Obstructive Sleep Apnea

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      https://www.riss.kr/link?id=A101610615

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      다국어 초록 (Multilingual Abstract)

      Background and Objectives We aimed to evaluate pre-operative factors for patients with obstructive sleep apnea (OSA) and determine the correlation these factors have with the improvement of daytime sleepiness based on the change of Epworth Sleepiness ...

      Background and Objectives We aimed to evaluate pre-operative factors for patients with obstructive sleep apnea (OSA) and determine the correlation these factors have with the improvement of daytime sleepiness based on the change of Epworth Sleepiness Scale (ESS) score before and after uvulopalatal flap (UPF).
      Subjects and Method Twenty-two patients with OSA who had received UPF surgery were enrolled in the study. We checked age, body mass index (BMI), size of tonsils, and position of palate. Using the Muller maneuver, we quantified the degree of obstruction at the velopharynx and the tongue base level. The cephalometric variables were checked by X-ray. Apnea-hypopnea index, respiratory distress index, and lowest oxygen saturation were obtained by portable monitoring. Finally, we obtained ESS score before and after UPF. The correlation between the aforementioned pre-operative factors and changes in ESS score was evaluated.
      Results A significant correlation was observed between the change in ESS score and patients’ age (R=0.168, p=0.031), BMI (R=0.642, p=0.004), and posterior airway space (PAS)(R=0.378, p=0.029). Patients who were older than 40 years old (p=0.030), obese patients with BMI≥25.0 (p=0.001), and those who had reported severe daytime sleepiness before surgery (pre-operative ESS score >10, p<0.01) reported greater improvement of daytime sleepiness after UPF.
      Conclusion We propose age, BMI, and wider PAS as predictors for greater improvement of daytime sleepiness after UPF in patients with OSA.

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      참고문헌 (Reference) 논문관계도

      1 최장원, "폐쇄성 수면무호흡증 환자에서 수면다원검사 결과와 약물유도수면내시경을 이용해 관찰된 폐쇄 부위의 연관성에 대한 분석" 대한이비인후과학회 56 (56): 346-353, 2013

      2 이현민, "폐쇄성 수면무호흡증 환자에서 구개수구개피판술과 구개근절제술의 수술 결과에 대한 비교 분석" 대한이비인후과학회 54 (54): 467-472, 2011

      3 강일규, "폐쇄성 수면 무호흡증 환자에서 수면내시경을 이용한 폐쇄부위의 관찰" 대한이비인후과학회 50 (50): 225-228, 2007

      4 Gislason T, "Uvulopalatopharyngoplasty in the sleep apnea syndrome. Predictors of results" 114 (114): 45-51, 1988

      5 Boot H, "Uvulopalatopharyngoplasty for the obstructive sleep apnoea syndrome: value of polysomnography, Mueller manoeuvre and cephalometry in predicting surgical outcome" 22 (22): 504-510, 1997

      6 Neruntarat C, "Uvulopalatal flap for obstructive sleep apnea: shortterm and long-term results" 121 (121): 683-687, 2011

      7 Schoen LS, "Upper-airway surgery for treating obstructive sleep apnea. Measuring and predicting success" 113 (113): 850-853, 1987

      8 Ryan CF, "Upper airway measurements predict response to uvulopalatopharyngoplasty in obstructive sleep apnea" 100 (100): 248-253, 1990

      9 Koutsourelakis I, "Surgery for obstructive sleep apnea: sleep endoscopy determinants of outcome" 122 (122): 2587-2591, 2012

      10 Martinez D, "Repeating administration of Epworth Sleepiness Scale is clinically useful" 15 (15): 763-773, 2011

      1 최장원, "폐쇄성 수면무호흡증 환자에서 수면다원검사 결과와 약물유도수면내시경을 이용해 관찰된 폐쇄 부위의 연관성에 대한 분석" 대한이비인후과학회 56 (56): 346-353, 2013

      2 이현민, "폐쇄성 수면무호흡증 환자에서 구개수구개피판술과 구개근절제술의 수술 결과에 대한 비교 분석" 대한이비인후과학회 54 (54): 467-472, 2011

      3 강일규, "폐쇄성 수면 무호흡증 환자에서 수면내시경을 이용한 폐쇄부위의 관찰" 대한이비인후과학회 50 (50): 225-228, 2007

      4 Gislason T, "Uvulopalatopharyngoplasty in the sleep apnea syndrome. Predictors of results" 114 (114): 45-51, 1988

      5 Boot H, "Uvulopalatopharyngoplasty for the obstructive sleep apnoea syndrome: value of polysomnography, Mueller manoeuvre and cephalometry in predicting surgical outcome" 22 (22): 504-510, 1997

      6 Neruntarat C, "Uvulopalatal flap for obstructive sleep apnea: shortterm and long-term results" 121 (121): 683-687, 2011

      7 Schoen LS, "Upper-airway surgery for treating obstructive sleep apnea. Measuring and predicting success" 113 (113): 850-853, 1987

      8 Ryan CF, "Upper airway measurements predict response to uvulopalatopharyngoplasty in obstructive sleep apnea" 100 (100): 248-253, 1990

      9 Koutsourelakis I, "Surgery for obstructive sleep apnea: sleep endoscopy determinants of outcome" 122 (122): 2587-2591, 2012

      10 Martinez D, "Repeating administration of Epworth Sleepiness Scale is clinically useful" 15 (15): 763-773, 2011

      11 Doghramji K, "Predictors of outcome for uvulopalatopharyngoplasty" 105 (105): 311-314, 1995

      12 Petri N, "Predictive value of Müller maneuver, cephalometry and clinical features for the outcome of uvulopalatopharyngoplasty. Evaluation of predictive factors using discriminant analysis in 30 sleep apnea patients" 114 (114): 565-571, 1994

      13 Riley R, "Palatopharyngoplasty failure, cephalometric roentgenograms, and obstructive sleep apnea" 93 (93): 240-244, 1985

      14 Larsson H, "Long-time followup after UPPP for obstructive sleep apnea syndrome. Results of sleep apnea recordings and subjective evaluation 6 months and 2 years after surgery" 111 (111): 582-590, 1991

      15 deBerry-Borowiecki B, "Indications for palatopharyngoplasty" 111 (111): 659-663, 1985

      16 Katsantonis GP, "Further evaluation of uvulopalatopharyngoplasty in the treatment of obstructive sleep apnea syndrome" 93 (93): 244-250, 1985

      17 Fujita S, "Evaluation of the effectiveness of uvulopalatopharyngoplasty" 95 (95): 70-74, 1985

      18 Friedman M, "Clinical staging for sleep-disordered breathing" 127 (127): 13-21, 2002

      19 Powell N, "A reversible uvulopalatal flap for snoring and sleep apnea syndrome" 19 (19): 593-599, 1996

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