한국 임산부의 혈청매독검사에 관한 고찰 = Studies of Serologic Test for Syphilis in Korean Pregneant Women -The Problem of Syphilis in Pregnancy as Seen at Severance Hospital-

다국어 초록 (Multilingual Abstract)

It is well known that syphilis in pregnancy is injurious to mother and fetus. The prevention of prenatal syphilis y treatment of the infected mother with penicilin during pregnancy is one of the major triumphs in modern medicine. Siphilis in pregnancy has decreased in almost all countries in the world. The trepoema pallidum, the causative agent, is very sensitive to penicillin and registant strains have not been found yet. Neverthless there is still a vast reservoir of infection and an alarming amount of undiscovered syphilis in the population. Recent information, obtained by the Medical Clinics of North America for the years 1960 to 1961 shows that the total number of reported cases of infective syphilis has risen three times in United States. In Korea, there is little documentary evidence of increase of syphilis since 1963. The diagnosis and treatment of syphilis in pregnancy are the same as for any syphilitic person, except that here werare not only concerned with curing the pregnant woman but also hope to avoid congenital syphilis in the baby. In some cases we may be pressed for time and forced to modify our general rules of diagnosis and treatment, in an effort to avoid the birth of a syphilitic infant. In order to know the current pattern of syphilis among pregnant women, 2838 women who delivered at Severance Hospital from 1962 to June, 1966, were analysed and the following retults were obtained. 1. During the 4½ years from Jan. 1962 to June. 1966, the rate of positive V.D.R.L. test`s was 5.2%. The rate of biological false positive test among the positie V.D.R.L. tests was 54%. 2. 51% of the gravidas reeived a V.D.R.L. test during or after delivery. Only 20% of the positive cases received the test prior the 7th month of gestation. 3. The majority of the patients with positive v.D.R.L. and R.P.C.F. test were primigravidas 25-30 years in age. 4. 92% of the syphilitic pregnnt women had latent syphilis. 5. Either a stillbirth or a premature delivery was noted in 48% of the positive R.P.c.F. untreated cases. 83% of the premature infants died during the neontal period. There were no deaths among the term infants. 6. Emphasis is placed upon the necessity of finding and treating all cases of syphilis during pregnancy. 7. In addition to general deucations about syphilis, it is reommented that pre-marital seroligic tests for syphilis be requird by law.