Fabrication of polymer microlens for cell detection by light scattering = 광산란을 이용한 세포 검출을 위한 폴리머 마이크로렌즈의 제작

다국어 초록 (Multilingual Abstract)

In laser light scattering detection and laser-induced fluorescence detection, the focusing of the excitation laser beam into a focal point of the channel in a microfluidic chip is important to obtain the largest intensity, and consequently to obtain the light collected to the photodetector with a high efficiency. In this paper, we present a polydimethylsiloxane (PDMS) microfluidic chip consisting of an integrated PDMS microlens for cell detection based on laser light scattering. The PDMS micro lens was fabricated by the photoresist reflow and PDMS replica molding method. This fabrication technique is simple and has a good property in terms of the microlens and a high-dimensional accuracy. The PDMS microlens integrated on the PDMS microfluidic channel was verified to improve the laser light intensity, and consequently signal to noise ratio and sensitivity of laser light scattering detection using red blood cells (RBCs).

목차 (Table of Contents)

• Abstract
• Ⅰ. Introduction
• Ⅱ. Fabrication
• Ⅲ. Experimental Results
• Ⅳ. Conclusion
• Acknowledgement
• References