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      Rabies neutralizing antibody titers in Korean dogs and cats intended for overseas travel

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      https://www.riss.kr/link?id=A108639696

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      다국어 초록 (Multilingual Abstract)

      Animals imported from abroad are a cause of rabies outbreaks in many countries. Therefore, rabies serology testing for dogs and cats traveling abroad is an important measure to reduce the incidence of rabies. Rabies virus antibodies were measured in sera collected from 2,367 dogs and 894 cats between 2017 and 2021. A serum sample with a value of 0.5 IU/mL or higher was considered a pass. The overall pass rates for rabies virus were 96.4% in dogs and 98.4% in cats. The mean rabies virus neutralization assay titers were higher in cats than in dogs and in female than in male animals. According to age, 6-year-old dogs and 9-year-old cats had the highest virus neutralization assay titers. Of the failure cases, 53.0% (53/100) were dogs or cats less than 1 year old. Although the average failure rates in dogs and cats were low at 3.5% and 1.6%, respectively, the factors influencing failure were age and vaccine manufacturer. Therefore, it is necessary to observe the vaccination interval and timing of blood collection after boosting.
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      Animals imported from abroad are a cause of rabies outbreaks in many countries. Therefore, rabies serology testing for dogs and cats traveling abroad is an important measure to reduce the incidence of rabies. Rabies virus antibodies were measured in s...

      Animals imported from abroad are a cause of rabies outbreaks in many countries. Therefore, rabies serology testing for dogs and cats traveling abroad is an important measure to reduce the incidence of rabies. Rabies virus antibodies were measured in sera collected from 2,367 dogs and 894 cats between 2017 and 2021. A serum sample with a value of 0.5 IU/mL or higher was considered a pass. The overall pass rates for rabies virus were 96.4% in dogs and 98.4% in cats. The mean rabies virus neutralization assay titers were higher in cats than in dogs and in female than in male animals. According to age, 6-year-old dogs and 9-year-old cats had the highest virus neutralization assay titers. Of the failure cases, 53.0% (53/100) were dogs or cats less than 1 year old. Although the average failure rates in dogs and cats were low at 3.5% and 1.6%, respectively, the factors influencing failure were age and vaccine manufacturer. Therefore, it is necessary to observe the vaccination interval and timing of blood collection after boosting.

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      참고문헌 (Reference)

      1 Zanoni RG, "Walking the dog and moving the cat : rabies serology in the context of international pet travel schemes" 152 : 561-568, 2010

      2 Hostnik P, "The modification of fluorescent antibody virus neutralization(FAVN)test for the detection of antibodies to rabies virus" 47 : 423-427, 2000

      3 Bourhy H, "Taxonomy and evolutionary studies on lyssaviruses with special reference to Africa" 60 : 277-282, 1993

      4 Kim HH, "Serosurvey of rabies virus, canine distemper virus, parvovirus, and influenza virus in military working dogs in Korea" 80 : 1424-1430, 2018

      5 Gilbert AT, "Rabies virus vectors and reservoir species" 37 : 371-384, 2018

      6 Raybern C, "Rabies in a dog imported from Egypt: Kansas, 2019" 1374-1377, 2020

      7 양동근 ; 김하현 ; 이은진 ; 유재영 ; 김종택 ; 안상진, "Rabies immune status of raccoon dogs residing in areas where rabies bait vaccine has been distributed" 대한백신학회 8 (8): 132-135, 2019

      8 Fooks AR, "Rabies" 3 : 17091-, 2017

      9 Shiraishi R, "Neutralizing antibody response in dogs and cats inoculated with commercial inactivated rabies vaccines" 76 : 605-609, 2014

      10 Cliquet F, "Neutralising antibody titration in 25,000 sera of dogs and cats vaccinated against rabies in France, in the framework of the new regulations that offer an alternative to quarantine" 22 : 857-866, 2003

      1 Zanoni RG, "Walking the dog and moving the cat : rabies serology in the context of international pet travel schemes" 152 : 561-568, 2010

      2 Hostnik P, "The modification of fluorescent antibody virus neutralization(FAVN)test for the detection of antibodies to rabies virus" 47 : 423-427, 2000

      3 Bourhy H, "Taxonomy and evolutionary studies on lyssaviruses with special reference to Africa" 60 : 277-282, 1993

      4 Kim HH, "Serosurvey of rabies virus, canine distemper virus, parvovirus, and influenza virus in military working dogs in Korea" 80 : 1424-1430, 2018

      5 Gilbert AT, "Rabies virus vectors and reservoir species" 37 : 371-384, 2018

      6 Raybern C, "Rabies in a dog imported from Egypt: Kansas, 2019" 1374-1377, 2020

      7 양동근 ; 김하현 ; 이은진 ; 유재영 ; 김종택 ; 안상진, "Rabies immune status of raccoon dogs residing in areas where rabies bait vaccine has been distributed" 대한백신학회 8 (8): 132-135, 2019

      8 Fooks AR, "Rabies" 3 : 17091-, 2017

      9 Shiraishi R, "Neutralizing antibody response in dogs and cats inoculated with commercial inactivated rabies vaccines" 76 : 605-609, 2014

      10 Cliquet F, "Neutralising antibody titration in 25,000 sera of dogs and cats vaccinated against rabies in France, in the framework of the new regulations that offer an alternative to quarantine" 22 : 857-866, 2003

      11 양동군 ; 김하현 ; 이경기 ; 유재영 ; 서문홍 ; 조인수, "Mass vaccination has led to the elimination of rabies since 2014 in South Korea" 대한백신학회 6 (6): 111-119, 2017

      12 "Manual of Diagnostic Tests and Vaccines for Terrestrial Animals (OIE): Rabies (infection with rabies virus and other lyssaviruses)" OIE

      13 Banyard AC, "Introduction History of rabies control by vaccination" 37 : 305-322, 2018

      14 Jakel V, "Factors influencing the antibody response to vaccination against rabies" 131 : 431-437, 2008

      15 Kennedy LJ, "Factors influencing the antibody response of dogs vaccinated against rabies" 25 : 8500-8507, 2007

      16 Mansfield KL, "Factors affecting the serological response of dogs and cats to rabies vaccination" 154 : 423-426, 2004

      17 Wallace RM, "Elimination of dog-mediated human rabies deaths by 2030 : needs assessment and alternatives for progress based on dog vaccination" 4 : 9-, 2017

      18 Cliquet F, "Development of a fluorescent antibody virus neutralisation test(FAVN test)for the quantitation of rabies-neutralising antibody" 212 : 79-87, 1998

      19 Suzuki K, "Antibody response to an anti-rabies vaccine in a dog population under field conditions in Bolivia" 55 : 414-420, 2008

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