Presented in this paper, the data from a chromosome study of 222 patients referred for suspected chromosome aberrations, and of 83 normal persons. Karyotypes were obtained using short-term blood culture, G-banding methods and Q-banding method.
Of the...
Presented in this paper, the data from a chromosome study of 222 patients referred for suspected chromosome aberrations, and of 83 normal persons. Karyotypes were obtained using short-term blood culture, G-banding methods and Q-banding method.
Of these patients, 162 patients had normal chromosome complements; 60(27.0%) patients had chromosome abnormalities, 50%(30/60) had aberrations of chromosme number, the others 50%(30/60) had aberrations of chromosome structure. One normal person had balanced structural rearrangement.
In abnormal structures there pericentric inversion, reciprocal translocation. Robertsonian translocation, insertion, deletion, isochromosome and variant chromosomes.
Thus the results of the present study indicate the importance of cytogenetic evaluation in clinically abnormal patients.