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      Association between serum alanine aminotransferase level and obesity indices in Korean adolescents

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      https://www.riss.kr/link?id=A104552068

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      다국어 초록 (Multilingual Abstract)

      Purpose: To analyze the correlation between serum alanine aminotransferase (ALT) and obesity indices including body mass index (BMI), body fat percentage (BFP), total fat mass (FM), truncal fat mass (TFM), waist circumference (WC), and waist-to-height...

      Purpose: To analyze the correlation between serum alanine aminotransferase (ALT) and obesity indices including body mass index (BMI), body fat percentage (BFP), total fat mass (FM), truncal fat mass (TFM), waist circumference (WC), and waist-to-height ratio (WHtR) in Korean adolescents.
      Methods: This was a cross-sectional study based on data derived from the 2010–2011 Korean National Health and Nutrition Examination Surveys (KNHANES). Subjects were Korean adolescents aged 10–18 years (871 total; 475 boys and 396 girls) who participated in KNHANES.
      Results: In both sexes, BMI, FM, TFM, WC, and WHtR were higher when ALT levels were in the 4th quartile. In boys, there was a significant positive correlation between ALT level and BMI, BFP, FM, TFM, WC, and WHtR (r=0.55, P<0.0001 for BMI; r=0.52, P<0.0001 for BFP; r=0.58, P<0.0001 for FM; r=0.61, P<0.0001 for TFM; and r=0.56, P<0.0001 for WC; r=0.62, P<0.0001 for WHtR), and the correlation coefficient was higher than that in girls.
      Conclusion: Our results suggest a significant positive association between serum ALT level and obesity indices in male adolescents.

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      참고문헌 (Reference)

      1 박혜원, "한국 청소년의 체성분과 비만 그리고 당뇨병 발생에 미치는 영향" 대한비만학회 22 (22): 137-144, 2013

      2 노한내, "한국 소아 청소년에서 비만 및 대사 이상의 유병률" 대한소아소화기영양학회 12 (12): 207-214, 2009

      3 황성욱, "소아 비만증에서 비알코올성 지방간염의 유병률" 대한소아과학회 48 (48): 13-20, 2005

      4 Hsieh SD, "Waist-to-height ratio, a simple and practical index for assessing central fat distribution and metabolic risk in Japanese men and women" 27 : 610-616, 2003

      5 Weili Y, "Waist-to-height ratio is an accurate and easier index for evaluating obesity in children and adolescents" 15 : 748-752, 2007

      6 Savva SC, "Waist circumference and waist-to-height ratio are better predictors of cardiovascular disease risk factors in children than body mass index" 24 : 1453-1458, 2000

      7 Wallace TM, "Use and abuse of HOMA modeling" 27 : 1487-1495, 2004

      8 Liu Q, "The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD)" 9 : 42-, 2010

      9 Schneider HJ, "The predictive value of different measures of obesity for incident cardiovascular events and mortality" 95 : 1777-1785, 2010

      10 Ibrahim MM, "Subcutaneous and visceral adipose tissue: structural and functional differences" 11 : 11-18, 2010

      1 박혜원, "한국 청소년의 체성분과 비만 그리고 당뇨병 발생에 미치는 영향" 대한비만학회 22 (22): 137-144, 2013

      2 노한내, "한국 소아 청소년에서 비만 및 대사 이상의 유병률" 대한소아소화기영양학회 12 (12): 207-214, 2009

      3 황성욱, "소아 비만증에서 비알코올성 지방간염의 유병률" 대한소아과학회 48 (48): 13-20, 2005

      4 Hsieh SD, "Waist-to-height ratio, a simple and practical index for assessing central fat distribution and metabolic risk in Japanese men and women" 27 : 610-616, 2003

      5 Weili Y, "Waist-to-height ratio is an accurate and easier index for evaluating obesity in children and adolescents" 15 : 748-752, 2007

      6 Savva SC, "Waist circumference and waist-to-height ratio are better predictors of cardiovascular disease risk factors in children than body mass index" 24 : 1453-1458, 2000

      7 Wallace TM, "Use and abuse of HOMA modeling" 27 : 1487-1495, 2004

      8 Liu Q, "The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD)" 9 : 42-, 2010

      9 Schneider HJ, "The predictive value of different measures of obesity for incident cardiovascular events and mortality" 95 : 1777-1785, 2010

      10 Ibrahim MM, "Subcutaneous and visceral adipose tissue: structural and functional differences" 11 : 11-18, 2010

      11 Olynyk JK, "Serum alanine aminotransferase, metabolic syndrome, and cardiovascular disease in an Australian population" 104 : 1715-1722, 2009

      12 Schwimmer JB, "SAFETY study: alanine aminotransferase cutoff values are set too high for reliable detection of pediatric chronic liver disease" 138 : 1357-1364, 2010

      13 Lin YC, "Risk factors for liver steatosis in obese children and adolescents" 51 : 149-154, 2010

      14 Yoo J, "Relationship between insulin resistance and serum alanine aminotransferase as a surrogate of NAFLD (nonalcoholic fatty liver disease) in obese Korean children" 81 : 321-326, 2008

      15 Park HS, "Relation between elevated serum alanine aminotransferase and metabolic syndrome in Korean adolescents" 82 : 1046-1051, 2005

      16 Helba M, "Pediatric body composition analysis with dual-energy X-ray absorptiometry" 39 : 647-656, 2009

      17 Clark JM, "Nonalcoholic fatty liver disease" 122 : 1649-1657, 2002

      18 Leamy AK, "Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease" 52 : 165-174, 2013

      19 Sweeting HN, "Measurement and definitions of obesity in childhood and adolescence: a field guide for the uninitiated" 6 : 32-, 2007

      20 Burns CJ, "Liver enzyme activity and body mass index" 38 : 1248-1252, 1996

      21 Ministry of Health & Welfare, "Korea Health Statistics 2010: The fifth Korea National Health and Nutrition Examination Survey (KNHANES V-5)" Ministry of Health & Welfare, Korea Centers for Disease Control and Prevention 2011

      22 Aigner E, "Iron stores, liver transaminase levels and metabolic risk in healthy teenagers" 40 : 155-163, 2010

      23 Perlemuter G, "Independent and opposite associations of trunk fat and leg fat with liver enzyme levels" 28 : 1381-1388, 2008

      24 Festi D, "Hepatic steatosis in obese patients: clinical aspects and prognostic significance" 5 : 27-42, 2004

      25 Monteiro PA, "Freitas Junior IF. Body composition variables as predictors of NAFLD by ultrasound in obese children and adolescents" 14 : 25-, 2014

      26 Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, "Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)" 285 : 2486-2497, 2001

      27 Robinson D, "Effect of body mass and other factors on serum liver enzyme levels in men attending for well population screening" 26 (26): 393-400, 1989

      28 Grotti Clemente AP, "Cut-off values of visceral adiposity to predict NAFLD in Brazilian obese adolescents" 2013 : 724781-, 2013

      29 이강건, "Cut-Off Values of Visceral Fat Area and Waist-to-Height Ratio: Diagnostic Criteria for Obesity-Related Disorders in Korean Children and Adolescents" 연세대학교의과대학 53 (53): 99-105, 2012

      30 Brann LS., "Classifying preadolescent boys based on their weight status and percent body fat produces different groups" 108 : 1018-1022, 2008

      31 Choi JW., "Association between elevated serum hepatic enzyme activity and total body fat in obese humans" 33 : 257-264, 2003

      32 Deutsch M, "Androgyny in fat patterning is associated with obesity in adolescents and young adults" 12 : 275-286, 1985

      33 Loomba R, "Advances in pediatric nonalcoholic fatty liver disease" 50 : 1282-1293, 2009

      34 Eknoyan G., "Adolphe Quetelet (1796-1874): the average man and indices of obesity" 23 : 47-51, 2008

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-15 학술지명변경 한글명 : Korean Journal of Pediatrics -> Clinical and Experimental Pediatrics
      외국어명 : Korean Journal of Pediatrics -> Clinical and Experimental Pediatrics
      KCI등재
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2019-07-16 학회명변경 한글명 : 대한소아과학회 -> 대한소아청소년과학회 KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2009-01-30 학술지명변경 한글명 : 소아과 -> Korean Journal of Pediatrics KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2003-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2002-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2000-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.18 0.18 0.16
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.17 0.2 0.369 0.06
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