Rifampin이 鷄胎의 組織分化 및 成長에 미치는 影響에 關한 硏究 = Effects of Rifampin on the Growth of Various Organs in Chick Embryos

다국어 초록 (Multilingual Abstract)

This is a study of the effect of Rifampin on the chicken embryo, involving an analysis of the growth of body weight, brain, heart, lung, liver, and kidney. By using the growth formula in varying amounts, its effect on specific growth rate, growth power, and the initial velocity of growth was carefully determined.
Moreover, by using a relative growth formula we have compared the coefficient of relative growth and the growth gradient of various organs to body weight.
Results of this research are as follows:
1) Rifampin is an inhibiting factor to the growth of the chicken embryo. The 2mg injected group less effect than the 4mg injected group.
2) With the passage of time, growth rate was increased in the following:
a) body weight of the control group and the 2mg injected group;
b) the liver of the control group and 4mg injected group;
c)the lung and kidney of all groups.
However, the passage of time showed a decrease in the following:
a) the body weight and liver of the 4mg injected group; and
b) the brain and heart of all groups.
3) In terms of specific growth rate, all groups showed a tendency toward steady decrease, forming a concave curve line downward. The one exception was the lung of the control group which increased until the fifteenth day.
4) As for the coefficient of relative growth of the various organs to body weight. the kidneys of the control group, the liver and kidneys of the 2mg inected group, and the brain, heart, and lungs of the 4mg injected group showed positive allometry. However, the remainder showed negative allometry.
5) A study of the growth gradient reveals that the liver of the control group and the 2mg injected group, and kidney of the 2mg injected group and the 4mg injected group have a growth center on the 12th day, while the heart of the 2mg injected group has its growth center on the 13th day.
The brain of the 2mg injected group and the heart of the 4mg injected group have their growth center on the 14th day; the brain and heart of the control group have theirs on the 15th day. For others the growth center occurs on the 18th day.