옻나무 (Rhus verniciflua Stokes) 추출물의 알코올대사 효소활성에 미치는 영향

다국어 초록 (Multilingual Abstract)

Alcohol oxidation activities and optimization of extraction conditions of Rrhus verniciflua Stokes (RVS) extract were evaluated for the development of a functional biomaterial for improving liver function. When alcohol oxidation activities of RVS was analyzed, the Rrhus verniciflua Stokes bark (RVSB) were higher than the Rrhus verniciflua Stokes heartwood (RVSH). Alcohol oxidation activity value of RVSB increased in a concentrationdependent manner. In the comparative analysis between Hovenia dulcis Thunb (HDT) and Alnus japonica Steud (AJS) which was reported as a alcohol oxidation material, alcohol oxidation activity is much higher than the others. The experimental conditions were optimized for alcohol oxidation-active components production from RVSB. The extraction conditions such as temperature, time, pH and particle size were performed. It was recommended to extract the alcohol oxidation-active components from RVSB by hot water (pH 7.0) at 85℃ for 8 hours.

목차 (Table of Contents)

• Abstract
• 서론
• 재료 및 방법
• 결과 및 고찰
• REFERENCES

참고문헌 (Reference)

1 최원식, "한국산 옻나무로부터 추출ㆍ분리한 생리활성 물질들의 항산화 효과 및 세포독성" 한국응용생명화학회 45 (45): 168-172, 2002

2 강배광, "채소의 용매분획 추출물들이 Saccharomyces cerevisiae의 alcohol dehydrogenase 활성에 미치는 영향" 한국식품과학회 34 (34): 244-248, 2002

3 전흥재, "우루시올-에탄올 수분산 미립자의 자궁경부암세포에 대한 독성효과" 한국약제학회 34 (34): 23-27, 2004

4 안은미, "옻나무(Rhus verniciflua) 목질부에서 분리한 화합물의 항산화활성" 한국응용생명화학회 50 (50): 358-361, 2007

5 전원경, "옻나무 추출물이 식이에 의한 비만유도 C57BL/6 mouse에 미치는 영향" 한국생약학회 34 (34): 339-343, 2003

6 양성운, "모델시스템과 가열우육에서 옻나무 추출물의 항산화 효과" 한국축산식품학회 25 (25): 189-195, 2005

7 Tottmar, S. O., "The subcellular distribution and properties of aldehyde dehydrogenase in rat liver" 135 : 577-581, 1973

8 Marshall, E. K., "The metabolism of ethyl alcohol" 109 : 431-, 1953

9 Cho, Y. S., "The effects of Rhus verniciflua extracts on the cytotoxicity on cancer cells and E6 and E7 oncogenes of human papillomavirus type16" 32 : 1389-1395, 2000

10 Lee, J. C., "Screening of antioxidant and antimicrobial effects from Rhus verniciflua Stokes (RVS) ethanolic extract" 9 : 139-145, 2000

11 Dool, R., "Quantitative estimates of avoidable risks of cnacer in the Unitede States today" 66 : 1192-, 1981

12 Choi, J. Y., "Probable reaction mechanism of rat liver cytosolic ALDH" 26 : 26-33, 1993

13 Kim, I. W., "Isolation of antioxidative components from the bark of Rhus verniciflua Stokes screened from some chinese medicinal plants" 31 : 855-863, 1999

14 Na, C. S., "In vitro Cytotoxin Activity of Urushiol in the Sap of Rhus verniciflua STOKES" 87 : 260-269, 1998

15 Fernald, M. I., "Gray's manual of botany 8th ed" 976-, 1950

16 Lee, Y. S., "Ethanol production from tapioca hydrolysate by batch and continuous cell retention cultures" 10 : 598-603, 1995

17 Paek, S. C., "Ethanol oxidation is accelerated by augmentation of malate-aspartate shuttle with aspartate" 25 : 137-143, 1993

18 Park, S. Y., "Direct ethanol production from starch substrate by polyploidy recombinant yeast secreting both α-amylase and glucoamylase" 2 : 604-612, 1996

19 Hong, D. H., "Cytotoxicity of urushiol isolated from sap of Korean lacquer tree (Rhus verniciflua Stokes)" 22 : 638-641, 2000

20 An, S. W., "Comparison of hepatic detoxification activity and reducing serum alcohol concentration of Hovenia dulsis THUNB and Alnus japonica Steud" 7 : 263-268, 1999

21 Shin, M. K., "Coloured Limsangbonchohak" Nam-San Dang 165-, 1986

22 Kim, C. I., "Cause and effect of hangover" 4 : 26-30, 1999

23 Lim, K. T., "Antioxidative effects of ethanol extracts from Rhus verniciflua Stokes (RVS) on mouse whole brain cells" 29 : 1248-1254, 1997

24 Lim, K. T., "Antioxidant activity of a Rhus verniciflua Stokes ethanol extract" 39 : 229-237, 2001

25 Roker, E., "Alcohol dehydrogenase from bakers yeast" 1 : 500-506, 1955