Normal 2-Dimensional Strain Values of the Left Ventricle: A Substudy of the Normal Echocardiographic Measurements in Korean Population Study

다국어 초록 (Multilingual Abstract)

Background: It is important to understand the distribution of 2-dimensional strain values in normal population. We performeda multicenter trial to measure normal echocardiographic values in the Korean population.
Methods: This was a substudy of the Normal echOcardiogRaphic Measurements in KoreAn popuLation (NORMAL) study.
Echocardiographic specialists measured frequently used echocardiographic indices in healthy people according to a standardizedmethod at 23 different university hospitals. The strain values were analyzed from digitally stored images.
Results: Of a total of 1003 healthy participants in NORMAL study, 2-dimensional strain values were measured in 501 subjects(265 females, mean age 47 ± 15 years old) with echocardiographic images only by GE echocardiographic machines. Interventricularseptal thickness, left ventricular (LV) posterior wall thickness, systolic and diastolic LV dimensions, and LV ejectionfraction were 7.5 ± 1.0 mm, 7.4 ± 1.0 mm, 29.9 ± 2.8 mm, 48.9 ± 3.6 mm, and 62 ± 4%, respectively. LV longitudinal systolicstrain (LS) values of apical 4-chamber (A4C) view, apical 3-chamber (A3C) view, apical 2-chamber (A2C) view, and LV global LS(LVGLS) were -20.1 ± 2.3, -19.9 ± 2.7, -21.2 ± 2.6, and -20.4 ± 2.2%, respectively. LV longitudinal systolic strain rate (LVLSR)values of the A4C view, A3C view, A2C view, and LV global LSR (LVGLSR) were -1.18 ± 0.18, -1.20 ± 0.21, -1.25 ± 0.21, and-1.21 ± 0.21-s, respectively. Females had lower LVGLS (-21.2 ± 2.2% vs. -19.5 ± 1.9%, p < 0.001) and LVGLSR (-1.25 ± 0.18-svs. -1.17 ± 0.15-s, p < 0.001) values than males.
Conclusion: We measured LV longitudinal strain and strain rate values in the normal Korean population. Since considerablegender differences were observed, normal echocardiographic cutoff values should be differentially applied based on sex.

참고문헌 (Reference)

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