Epithelioid blue nevus (EBN) is a rare but distinctive histologic variant of blue nevus that has been described in patients with Carney complex, an autosomal-dominant multiple neoplasia syndrome. Clinically, EBN is typically characterized as small (le...
Epithelioid blue nevus (EBN) is a rare but distinctive histologic variant of blue nevus that has been described in patients with Carney complex, an autosomal-dominant multiple neoplasia syndrome. Clinically, EBN is typically characterized as small (less than 1 cm), darkly pigmented, dome-shaped nodules or, less commonly, as macules on the skin or mucosa. Recently, cases of EBN have been reported in patients without Carney complex. On histologic findings, variably pigmented, large epithelioid melanocytes with vesicular nuclei and a small number of melanophages that are sometimes associated with a few pigmented, spindle, and dendritic cells can be seen. A 40-year-old male presented with a solitary steel bluish well demarcated 6 x 4 mm sized nodule with central umbilication on the left arm without any clinical evidence of Carney complex. On dermoscopy, oval shaped, diffuse structureless area with steel-blue pigmentation and a central round dimple with whitish rim were seen. In the absence of any other dermoscopic structures, a clinical diagnosis of blue nevus was established. Histologic findings showed a wedge shaped symmetrical structure composed of heavily pigmented cells involving the dermis. On higher magnification, epithelioid melanocytes with large cytoplasm and abundant melanin within their cytoplasm were seen. The diagnosis of EBN was made. Herein, we report a case of EBN for whom dermoscopy was used as a helpful diagnostic tool.