자궁경부종양의 진단 및 치료적 원추절제술에 대한 임상적 고찰 = Clinical outcome of diagnostic and therapeutic knife Conization for Cervical Intraepithelial Neoplasia

다국어 초록 (Multilingual Abstract)

Purpose : To evaluate clinical efficacy of diagnosis and treatment using knife conization for cervical intraepithelial neoplasia.
Subject and Methods : We have treated 50 women, then were divided into diagnostic and therapeutic conization group and then indication of conization, cytology, directed biopsy, cone margin and residual lesion of each group were compared respectively.
Results Diagnostic conization was performed in 22 patients who were upper limit of the lesion was invisible, squamocolumnar junction was not seen, High-grade squamous intraepithelial lesions or invasive cancer was suspected. four cases of follow-up group had negative cone margin and no recurrence. Eighteen cases of positive cone margin were performed repeat conization and immediate total abdominal hysterectomy. There was no recurrence after repeat conization and hysterectomy. Therapeutic conization was performed in such 28 cases as upper limit of the lesion was visible, squamocolumnar junction was seen and invasive cancer was ruled out. Twentyfive cases of therapeutic conization group had negative cone margin and were follow up. Three cases of positive cone margin were performed repeat conization and were follow up. There was no recurrence after repeat conization.
Conclusions : The knife conization was useful to detect· unexpected invasive cervical cancer and revealed excellent therapuetic & diagnostic effects for cervical intraepithelial neoplasia. Careful follow up was needed after knife conization of cervical intraepithelial neoplasia because of the possibile residual disease even though histologic proven negative cone margin.