우리나라 60세 이상 폐경 후 여성에서 추정 근감소증과 우울증상 간 연관성 = Association Between Possible Sarcopenia and Depressive Symptoms in Postmenopausal Women Aged 60 and Over in Korea

다국어 초록 (Multilingual Abstract)

-Purpose:“Possible Sarcopenia”, defined by the Asian Working Group for Sarcopenia (AWGS) in 2019, identifies early-stage sarcopenia, assessed by grip strength or physical function in primary care settings. Previous studies have shown a significant association between sarcopenia and depression, but the relationship in postmenopausal women across different age groups remains unexplored. This study analyzes the association between possible sarcopenia and depressive symptoms in postmenopausal women, considering socioeconomic factors and chronic diseases.
-Methods:We analyzed data from the Korea National Health and Nutrition Examination Survey from 2014 to 2022 including 3,773 postmenopausal women aged 60 and above (mean age: 69.7 years). Possible sarcopenia was classified using AWGS 2019 guidelines (grip strength: men ＜28kg, women ＜18kg). Depressive symptoms were assessed with the Patient Health Questionnaire-9 (PHQ-9), with scores of 10 or higher indicating depression. Multiple logistic regression was used to analyze the effect of possible sarcopenia on depressive symptoms, adjusting for income, education, marital status, lifestyle factors, and chronic diseases.
-Results:There were 291 participants with depressive symptoms, accounting for 7.7% of the total participants, and 949 participants (25.2%) had probable sarcopenia. Participants with possible sarcopenia had a higher risk of depressive symptoms (OR=1.668, 95% CI: 1.173-2.370, p=0.004), which remained significant after adjusting for covariates. The association was stronger in the 60-69 age group (OR=2.618, p=0.001) and not significant in the 70-80 age group. Possible sarcopenia significantly impacts depressive symptoms in postmenopausal women aged 60 and above, particularly in the 60-69 age group.
-Conclusion:These findings highlight the importance of early management of sarcopenia to reduce depressive symptoms and suggest the need for integrated mental health strategies for postmenopausal women.