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      섬오가피의 추출 조건에 따른 페놀성 성분 함량 변화 = Changes in the Contents of Phenolic Components in the Stem of Acanthopanax koreanum Depending on Extracting Batches

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      https://www.riss.kr/link?id=A106519068

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      다국어 초록 (Multilingual Abstract)

      This study compared the contents of phenolic components depending on the extracting conditions of Acanthopanax koreanum stem to provide basic information for developing Acanthopanax koreanum-based functional foods. Our findings show that the content of total phenolic component peaked at 16 hours of extraction (WAK-16, 7.22%) and when water extracted at 100oC. However, 11-hours water extraction (WAK-11) showed highest eleutheroside B concentration of 1.32%, a main component of A. koreanum, and the level of chlorogenic acid concentration was the highest when 1-hour water extraction (WAK-1) was conducted, being 2.12%. Moreover, highest concentration of eleutheroside E was observed in 16-hours water extraction (WAK-16) as 1.49%. With 60-hours water extraction (WAK-60), the content of syringaresinol, an active phenolic aglycon substance, concentration was the highest with the value of 0.10%. Isofraxidin showed the highest concentration of water extract(0.09%) for 20 hours (WAK-20) and 0.42% for sinapyl alcohol[16 hours (WAK-16)].
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      This study compared the contents of phenolic components depending on the extracting conditions of Acanthopanax koreanum stem to provide basic information for developing Acanthopanax koreanum-based functional foods. Our findings show that the content o...

      This study compared the contents of phenolic components depending on the extracting conditions of Acanthopanax koreanum stem to provide basic information for developing Acanthopanax koreanum-based functional foods. Our findings show that the content of total phenolic component peaked at 16 hours of extraction (WAK-16, 7.22%) and when water extracted at 100oC. However, 11-hours water extraction (WAK-11) showed highest eleutheroside B concentration of 1.32%, a main component of A. koreanum, and the level of chlorogenic acid concentration was the highest when 1-hour water extraction (WAK-1) was conducted, being 2.12%. Moreover, highest concentration of eleutheroside E was observed in 16-hours water extraction (WAK-16) as 1.49%. With 60-hours water extraction (WAK-60), the content of syringaresinol, an active phenolic aglycon substance, concentration was the highest with the value of 0.10%. Isofraxidin showed the highest concentration of water extract(0.09%) for 20 hours (WAK-20) and 0.42% for sinapyl alcohol[16 hours (WAK-16)].

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      참고문헌 (Reference)

      1 고성권, "한방생약학" 진영사 128-129, 2016

      2 안혜정, "오가피속 식물 잎의 식물화학 성분 비교" 대한약학회 61 (61): 90-95, 2017

      3 안혜정, "오가피속 식물 열매의 식물화학 성분 비교" 한국생약학회 48 (48): 5-9, 2017

      4 한국생약학교수협의회, "본초학" 대한약사회 305-308, 2004

      5 전국한의과대학 본초학교수, "본초학" 영림사 283-284, 1994

      6 Ovodov, Y. S., "Triterpenoidal glycosides of Eleuterococcus sessiliflorus leaves II" 1 : 618-622, 1971

      7 Song, Y. Y., "Therapeutic effect of syringin on adjuvant arthritis in rats and its mechanisms" 45 : 1006-1011, 2010

      8 Ovodov, Y. S., "The glycosides of Eleutherococcus senticosus Max I. Isolation and some properties of eleutherosides B and E" 1 : 3-7, 1996

      9 Li, F., "Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy" 39 : 199-207, 2017

      10 Liu, J., "Syringin prevents bone loss in ovariectomized mice via TRAF6 mediated inhibition of NF-κB and stimulation of PI3K/AKT" 42 : 43-50, 2018

      1 고성권, "한방생약학" 진영사 128-129, 2016

      2 안혜정, "오가피속 식물 잎의 식물화학 성분 비교" 대한약학회 61 (61): 90-95, 2017

      3 안혜정, "오가피속 식물 열매의 식물화학 성분 비교" 한국생약학회 48 (48): 5-9, 2017

      4 한국생약학교수협의회, "본초학" 대한약사회 305-308, 2004

      5 전국한의과대학 본초학교수, "본초학" 영림사 283-284, 1994

      6 Ovodov, Y. S., "Triterpenoidal glycosides of Eleuterococcus sessiliflorus leaves II" 1 : 618-622, 1971

      7 Song, Y. Y., "Therapeutic effect of syringin on adjuvant arthritis in rats and its mechanisms" 45 : 1006-1011, 2010

      8 Ovodov, Y. S., "The glycosides of Eleutherococcus senticosus Max I. Isolation and some properties of eleutherosides B and E" 1 : 3-7, 1996

      9 Li, F., "Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy" 39 : 199-207, 2017

      10 Liu, J., "Syringin prevents bone loss in ovariectomized mice via TRAF6 mediated inhibition of NF-κB and stimulation of PI3K/AKT" 42 : 43-50, 2018

      11 Cui, Y., "Syringin may exert sleep-potentiating effects through the NOS/NO pathway" 29 : 178-184, 2014

      12 Kim, B., "Syringin attenuates insulin resistance via adiponectin-mediated suppression of low-grade chronic inflammation and ER stress in high-fat diet-fed mice" 488 : 40-45, 2017

      13 Cho, S., "Syringaresinol protects against hypoxia / reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism" 6 : 43-55, 2015

      14 Byung-Hee Chung, "Syringaresinol causes vasorelaxation by elevating nitric oxide production through the phosphorylation and dimerization of endothelial nitric oxide synthase" 생화학분자생물학회 44 (44): 191-201, 2012

      15 Zhao, L. S., "Simulataneous determination of six constituents in the fruit of Acanthopanax sessiliflorus (Rupr. et maxim.) seem. by HPLC-UV" 7 : 500-502, 2014

      16 Zhang, A., "Protective effects of syringin against lipopolysaccharide-induced acute lung injury in mice" 209 : 252-257, 2017

      17 Yook, C. S., "Medicinal herbs of Acanthopanax in Asia" Kyungwon Media 1-174, 2001

      18 Miyazawa, M., "Inhibition of Helicobacter pylori motility by (+)-syringaresinol from unripe Japanese apricot" 29 : 172-173, 2006

      19 Lim, H., "Impressic acid from Acanthopanax koreanum, possesses matrix metalloproteinase-13 down-regulating capacity and protects cartilage destruction" 209 : 73-81, 2017

      20 Niu, H. S., "Hypoglycemic effect of syringin from Eleutherococcus senticosus in streptozotocin-induced diabetic rats" 74 : 109-113, 2008

      21 Gong, X., "Hepatoprotective effects of syringin on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice" 34 : 265-271, 2014

      22 Min-Ja Park, "Fermented Acanthopanax koreanum Root Extract Reduces UVB- and H2O2-Induced Senescence in Human Skin Fibroblast Cells" 한국미생물·생명공학회 26 (26): 1224-1233, 2016

      23 Ahn, J., "Eleutheroside E, an active component of Eleutherococcus senticosus, ameliorates insulin resistance in type 2 diabetic db/db mice" 2013 : 934183-, 2013

      24 He, C., "Eleutheroside E ameliorates arthritis severity in collagen-induced arthritis mice model by suppressing inflammatory cytokine release" 5 : 1533-1543, 2014

      25 김주원, "Effects of Korean ginseng berry on skin antipigmentation and antiaging via FoxO3a activation" 고려인삼학회 41 (41): 277-283, 2017

      26 Li, C., "Determination of eleutheroside B in antifatigue fraction of Acanthopanax senticosus by HPLC" 33 : 2800-2802, 2008

      27 Lall, N., "Cytotoxicity of syringin and 4-methoxycinnamyl alcohol isolated from Foeniculum vulgare on selected human cell lines" 29 : 1752-1756, 2015

      28 Lall, N., "Cytotoxicity of syringin and 4-methoxycinnamyl alcohol isolated from Foeniculum vulgare on selected human cell lines" 29 : 1752-1756, 2015

      29 Yook, C. S., "Asia Saeng-Yak-Do-Gam" Kyungwon media 359-362, 1997

      30 Choi, J., "Anti-inflammatory and antinociceptive effects of sinapyl alcohol and its glucoside syringin" 70 : 1027-1032, 2004

      31 정명기, "Acanthopanax koreanum Nakai modulates the immune response by inhibiting TLR 4-dependent cytokine production in rat model of endotoxic shock" 한국영양학회 7 (7): 460-465, 2013

      32 Wei, C., "Acanthoic acid inhibits LPS-induced inflammatory response in human gingival fibroblasts" 38 : 896-901, 2015

      33 Park, B. Y., "(-)-Syringaresinol inhibits proliferation of human promyelocytic HL-60 leukemia cells via G1 arrest and apoptosis" 8 : 967-973, 2008

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2005-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2004-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보학술지 유지 (등재후보1차) KCI등재후보
      2001-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.42 0.42 0.39
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.42 0.41 0.803 0.05
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