To investigate antitumor components of Korean higher fungi, the carpophores of Ganoderma lucidum were collected in Gyeong-gi Province and extracted with 0.1 N-NaOH solution. The extract was purified by dialyzing through Visking tube and a polysacchari...
To investigate antitumor components of Korean higher fungi, the carpophores of Ganoderma lucidum were collected in Gyeong-gi Province and extracted with 0.1 N-NaOH solution. The extract was purified by dialyzing through Visking tube and a polysaccharide fraction was obtained. The antitumor activity of the fraction was tested against sarcoma 180 implanted in mice. The tumor inhibition ratio of the polysaccharide fraction against the tumor was 87.6% in the doses of 50㎎/㎏/day for the period of ten days. The tumor in five of the 15 mice was completely regressed.