함초와 발효함초 추출물로부터 여드름에 유효한 화장품 소재개발 = Antimicrobial Activities of Fermented Salicornia herbacea Extracts Against Acne Vulgaris

다국어 초록 (Multilingual Abstract)

Purpose: This study aims to present a possibility of developing materials effective against acne vulgaris by analysing components of dried and fermented salicornia herbacea, their antimicrobial activity and NO(nitric oxide) scavenging activity. Methods: For the purpose, components and mineral contents of dried and fermented salicornia herbacea were measured according to a AOAC (Association of Official Analytical Chemists) method and specimen were extracted with uses of methanol and ethanol. Anti-microbial activity was tested against Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acnes by disc diffusion assay. Anti-inflammatory activity was NO scavenging activity measured. Results: The antimicrobial activity discovered from 20 mg/disc of fermented S. herbacea extract was presented as follows: 14.3±0.7 mm clear zone from S. aureus, 12.5±0.2 mm clear zone from S. epidermidis and 20.2±3.0 mm clear zone from P. acnes. It was discovered that P. acnes had the highest antimicrobial activity of the samples. The highest NO scavenging activity, 35.23±0.52%, was discovered from 10.0 mg/mL of fermented S. herbacea extracts. Conclusion: These results demonstrate that fermented S. herbacea, extract has the highest possibility to be developed as a material for acne cosmetics.