Chemical Constituents and Biological Activities of Cichorium intybus L.

다국어 초록 (Multilingual Abstract)

Continuation of a phytochemical study of Cichorium intybus L. (Astraceae) growing in Egypt, resulted in the isolation and identification of a new sesquiterpene lactone 3, 4-dihydrolactucin, in addition to the eight known compounds; kaempferol, isoscutellarin, cichoriin, umbelliferone, lupeol, lupeol acetate, β-sitosterol, and β-sitosterol-3-O-glucoside. Chemical structures of the isolated compounds were assigned based on different physical, chemical, and spectroscopic techniques including IR, UV, MS, 1D- and 2D-NMR spectra. Furthermore, the antimicrobial,
and spasmogenic activities of some fractions and isolates were also assessed.

참고문헌 (Reference)

1 "coumarins and flavonoids of Launaeatenuiloba Boiss grown in Egypt" 275-282,

2 "Twoguaianolides from Cichorium pumilum" 183-51984

3 "The antibacterial activity of some essentialoils and their combinations" 118-122, 1971

4 "The Pharmacognostical Study andPhytochemical Investigation of Certain Plants Belonging to FamilyCompositae Faculty of Pharmacy University of Alexandria" pharmacog (pharmacog): 1974

5 "Spectroscopic Methods in OrganicChemistry" McGraw-Hill Book Company 1980

6 "Spectral Data of Natural Products" Elsevierpublishing Co

7 "Sesquiterpene lactones from Lactuca tatarica" 45 (45): 365-368, 1997

8 "Professional Handbook of complementary medicines" Spring House Corporation 1999

9 "Pharmacological experiments on isolated organpreparations" 1970

10 "Optimizationof a quantitative HPLC determination of potentialy anticarcinogenicflavonoids in vegetables and fruits" and Venema 1591-1598, 1992

11 "Content ofpotentially anticarcinogenic flavonoids of 28 vegetables and 9fruits commonly consumed in the Netherlands" 2379-2383, 1992

12 "Chemical constituents of CirisumSyriacum and Chichorium intybus(Asteraceae) Growing in Egypt" 16 (16): 152-156, 2002

13 "Carbon-l3 NMR studies of flavonoids-III" -1397,

14 "A Sensible Guide to the use of Herbs Related to Remedies" 1992

15 "; A Reference Guide to MedicinalPlants" Duke UniversityPress 1990