The acute toxicity of rHu-EPO, newly developed recombinant erythropoietin, was tested in beagle dogs. rHu-EPO, when administered intravenously at 25, 000 IU/kg, did not cause any death. Also, rHu-EPO did not induce any change of body weight, foo...
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https://www.riss.kr/link?id=A106721268
조명행 ; 성하정 ; 김형식 ; 곽승준 ; 천선아 ; 임소영 ; 김원배 ; 김병문 ; 안병옥 ; 이병무 ; Cho, Myung-Hang ; Seong, Ha-Jung ; Kim, Hyung-Sik ; Kwack, Seung-Jun ; Chun, Sun-Ah ; Lim, So-Young ; Kim, Won-Bae ; Kim, Byoung-Moon ; Ahn, Byoung-Ok ; Lee, Byung-Mu
1996
Korean
SCOPUS,KCI등재,SCIE
학술저널
305-308(4쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
The acute toxicity of rHu-EPO, newly developed recombinant erythropoietin, was tested in beagle dogs. rHu-EPO, when administered intravenously at 25, 000 IU/kg, did not cause any death. Also, rHu-EPO did not induce any change of body weight, foo...
The acute toxicity of rHu-EPO, newly developed recombinant erythropoietin, was tested in beagle dogs. rHu-EPO, when administered intravenously at 25, 000 IU/kg, did not cause any death. Also, rHu-EPO did not induce any change of body weight, food intake and clinical signs compared to controls. There were no significant changes in hematological, urine analysis and pathological examination. These results showed that rHu-EPO did not induce any remarkable toxic response and the $LD_50$ was greater than 25, 000 IU/kg in beagle dogs.
대장균에서 발현된 인간 Cytochrome P450 1A1과 Rat NADPH-P450 Reductase와의 Fusion Protein의 효소 특성 연구
Behavioral Effects of Mianserin on the Developmental Toxicity of Cocaine