회농성 결절 홍반을 동반한 궤양성 대장염 1예 = A Case Report of Suppurative Erythema Nodosum in Ulcerative Colitis

다국어 초록 (Multilingual Abstract)

Ulcerative colitis(UC)is a disease that affects the mucosal lining of the colon. Epidemiologlcal studies revealed that UC is global in distribution and the incidence has risen in recent decades. The pathogenesis of UC, remains uncertain. However, recent studies have suggested that colonic environment, most notably bacteria flora, genetic susceptibility, mucosal defects, immunologic abnormalities, altered levels of specific cytokine and inflammatory mediators,and dietary factors are implicated. The major symptoms of ulcerative colitis include diarrher, abdominal pain, and hematochezia(rectal bleeding). Ulcerative colitis also may be complicated by many local and systemic disorders as extracolonic symptoms. Erythema nodosum is one of the most frequent dermatologic complications associated with ulcerative colitis. It is an acute, painful, rective skin inflammation of unknown cause. Physicians can disgnose clinically, since there is no accepted histological diagnostic criteria. Conventational therapy is preferred to control causative disease. We authors experienced a case of suppurative erythema nodosum on both shins of ulcerative colitis patient, which was treated with high dose corticosteroids and discharged with clinical improvement of dematologic manifiestation, coincidently controlled acute exacerbation of the bowel disease. So we report this case with a brief literature review.