The present investigation has been undertaken to elucidate the functional role of voarian steroids on the mechanism of oviduct differentiation during early embryonic development in rat.
The activity of alkaline phosphatase(ALPase) was measured in the...
The present investigation has been undertaken to elucidate the functional role of voarian steroids on the mechanism of oviduct differentiation during early embryonic development in rat.
The activity of alkaline phosphatase(ALPase) was measured in the oviduct tissue under different steroids treatment regime on day 9 pregnancy. The ALPase activity of the oviduct of pseudopregnant rat was compared with that of normal pregnant rat. The results of day 9 pregnancy rat oviduct clearly demonstrated that 17β-estradiol and progesterone were effective in pseudopregnant rat ovidut. In the ovary intact group the ALPase activity was similar in both of normal and psedudopregnant oviduct, but in the 17β-estradiol treated group the ALPase activity in normal pregnancy was significantly higher than that in pseudopregnancy. The effect of estrakiol on the normal pregnant rat oviduct was apparently found on day 3 and day 9 pregnancy.
This study, therefore, clearly demonstrates that 17β-estradiol is much potent in oviduct tissue differentiation. It is suggested that absence of 17β-estradiol effect on pseudopregnant rat oviduct is due to there is no embryo passing througth the oviduct.