주요우울장애 환자에서 일 년 이내 재입원에 영향을 미치는임상 요인: 일 대학병원 후향적 조사 = Clinical Characteristics of Patients with Major Depressive Disorder That Affect One-Year Rehospitalization Rate: A Retrospective Study in a University Hospital

다국어 초록 (Multilingual Abstract)

ObjectivezzThis study was designed to investigate the clinical characteristics of patients with major depressive disorder who were rehospitalized within a year in a naturalistic setting at a university hospital.
MethodszzInpatients with major depressive disorder patients were retrospectively investigated. Data on patients’ demographic factors, clinical variables-age, sex, education year, socioeconomic state, marital state, illness duration, length of stay, severity of illness, presence of psychotic features, number of past depressive episodes and hospitalization, family history, comorbidity-were collected. Use of antidepressants, antipsychotics, mood stabilizers and hypnotics were investigated.
ResultszzA total of 238 patients participated in the study. No significant differences were observed between one-year rehospitalized group and the non-rehospitalized group in demographic factors and clinical variables except for the number of previous psychiatric hospitalizations. The mean number of previous psychiatric hospitalization was significantly higher in the one-year rehospitalized group than the non-rehospitalized group (0.41±0.83 times vs. 0.23±0.83 times) (p=0.048). No significant differences in rehospitalized rates were observed among the disparate treatment types. One-year rehospitalization rate was significantly higher in patients who discontinued antidepressants than the patients who continued the antidepressants (15.9% vs. 0%) (p=0.002).
ConclusionzzThe present data suggest that the number of previous psychiatric hospitalizations is higher in patients who were rehospitalized within a year and the discontinuation of antidepressant might be an influencing factor. Further controlled studies are recommended to confirm our findings.

국문 초록 (Abstract)

흔히 정신건강의학과 진료 중에 만날 수 있는 주요우울장애 환자들 중 입원 환자들을 대상으로 재입원을 하는 환자들의 특징을 파악하고자 하였다. 본 연구에서 1년 이내 재입원을 한 환자들은 그렇지 않은 환자들에 비해 이전의 정신과적 입원횟수가 유의하게 높았다. 또한 항우울제의 종류와 약물치료의 종류에 따른 차이점을 비교하였으나 여러 대상군들 사이에 유의한 차이는 없었다. 또한 항우울제 중단을 할 경우 그렇지 않은 경우에 비해 재입원을 하는 경우가 유의하게 높았다. 이러한 결과들을 종합하였을 때 정신과적 입원의 과거력과 항우울제의 중단은 재입원을 예측하는 인자로서 임상적인 의의가 있고, 이외의 다른 요소들에 대한 추가적인 연구가 필요할 것으로 사료 된다.

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