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3 "Troglitazone, a peroxisome proliferator-activated receptor gamma (PPARgamma) ligand, selectively induces the early growth response-1 gene independently of PPARgamma" 278 : 5845-5853, 2003
4 "Troglitazone, a ligand for peroxisome proliferator-activated receptor gamma, inhibits chemicaly-induced aberrant crypt foci in rats" 92 : 396403-, 2001
5 "Troglita-zone, antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome prolifera-tor-activated receptor-gamma" 48 : 254260-, 1999
6 "Transdiffer-entiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha" 92 : 98569860-, 1995
7 "Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, inhibits growth and metas-tasis of HT-29 human colon cancer cells through diferentia-tion-promoting effects" 25 : 631639-, 2004
8 "The organization, promoter analysis, and expression of the human PPARgamma gene" 272 : 1877918789-, 1997
9 "Terminal diferentiation of human breast cancer through PPAR gamma" 1 : 465470-, 1998
10 "Synergistic effects of RXR {alpha} and PPAR{gamma} ligands to inhibit growth in hu-man colon cancer cells - phosphorylated RXR{alpha} is a critical target for colon cancer management 1" 2007
1 "tissue-specific regula-tor of an adipocyte enhancer. Genes Dev. 8" tonto (tonto): 1994a
2 "Use of the peroxisome proliferator-activated receptor (PPAR) gamma ligand troglitazone as treatment for refractory breast cancer: a phase I study" 79 : 391397-, 2003
3 "Troglitazone, a peroxisome proliferator-activated receptor gamma (PPARgamma) ligand, selectively induces the early growth response-1 gene independently of PPARgamma" 278 : 5845-5853, 2003
4 "Troglitazone, a ligand for peroxisome proliferator-activated receptor gamma, inhibits chemicaly-induced aberrant crypt foci in rats" 92 : 396403-, 2001
5 "Troglita-zone, antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome prolifera-tor-activated receptor-gamma" 48 : 254260-, 1999
6 "Transdiffer-entiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha" 92 : 98569860-, 1995
7 "Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, inhibits growth and metas-tasis of HT-29 human colon cancer cells through diferentia-tion-promoting effects" 25 : 631639-, 2004
8 "The organization, promoter analysis, and expression of the human PPARgamma gene" 272 : 1877918789-, 1997
9 "Terminal diferentiation of human breast cancer through PPAR gamma" 1 : 465470-, 1998
10 "Synergistic effects of RXR {alpha} and PPAR{gamma} ligands to inhibit growth in hu-man colon cancer cells - phosphorylated RXR{alpha} is a critical target for colon cancer management 1" 2007
11 "Stimula-tion of adipogenesis in fibroblasts by PPAR gamma 2" tonto (tonto): 1994b
12 "Rosiglitazone, a PPARgamma ligand, mo-dulates signal transduction pathways during the development of acute TNBS-induced colitis in rats" 562 : 247258-, 2007
13 "RS5444, a novel PPARgamma agonist, regu-lates aspects of the diferentiated phenotype in nontrans-formed intestinal epithelial cells" 251 : 1732-, 2006a
14 "Peroxisome proliferator-activated receptor gamma-mediated diferentiation: a muta-tion in colon cancer cells reveals divergent and cell type-specific mechanisms" 278 : 2266922677-, 2003b
15 "Peroxisome proliferator-activated receptor gamma recruits the positive transcription elongation factor b complex to activate transcription and promote adipogenesis" 20 : 14941505-, 2006
16 "Peroxisome proliferator-activated receptor gamma ligands suppress colon carcinogenesis induced by azoxyme-thane in mice" 124 : 361367-, 2003
17 "Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells" 162 : 331340-, 1999
18 "Peroxisome proliferator-activated receptor gamma induces growth arrest and differentiation markers of human colon cancer cells" 90 : 7580-, 1999
19 "Peroxisome proliferator-activated receptor gamma and transforming growth factor-beta pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22" 278 : 74317438-, 2003a
20 "Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice" 116 : 495499-, 2005
21 "Peroxisome proliferator-activated receptor expression and activation in normal human colonic epithelial cells and tubular adenomas" 40 : 198205-, 2005
22 "Peroxisome proliferator-activated recep-tor gamma promotes epithelial to mesenchymal transforma-tion by Rho GTPase-dependent activation of ERK1/2" 281 : 2457524587-, 2006b
23 "Peroxisome proliferator activated receptor gamma expression is reduced in the colonic mucosa of acromegalic patients" 87 : 24032406-, 2002
24 "PPARgamma3 mRNA: a distinct PPARgamma mRNA subtype transcribed from an independent promoter" 438 : 5560-, 1998
25 "PPARgamma as a new therapeutic target in inflammatory bowel diseases" 55 : 13411349-, 2006
26 "PPARalpha and PPARgamma activators direct a distinct tisue-specific transcriptional re-sponse via a PPRE in the lipoprotein lipase gene" 15 : 53365348-, 1996
27 "PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene" 15 : 351357-, 1995
28 "Novel high-afinity PPARgamma agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/ CIP1" 25 : 23042317-, 2006
29 "Mutational analysis of the peroxisome proliferator-activated receptor gamma gene in human malig-nancies" 61 : 53075310-, 2001
30 "Molecular recognition of faty acids 176 PPARγ in G.I. Epithelial Cells .by peroxisome proliferator-activated receptors" 3 : 397403-, 1999
31 "Loss-of-function mutations in PPAR gamma associated with human colon cancer" 3 : 799-804, 1999
32 "Ligands for peroxisome proliferator-activated re-ceptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats" 61 : 24242428-, 2001
33 "Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo" 58 : 33443352-, 1998
34 "Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma" 395 : 137143-,
35 "Ligand activation of peroxisome prolif-erator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via block-ade of the Tcf-4 activity" 9 : 513526-, 2002
36 "Intestinal-specific PPARgamma deficiency enhances tumorigenesis in ApcMin/+ mice" 119 : 2339-2346, 2006
37 "Induction of solid tumor diferentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma" 96 : 39513956-,
38 "Induction of differentiation and peroxisome prolif-erator-activated receptor gamma expression in colon cancer cell lines by troglitazone" 130 : 73-79, 2004
39 "Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PAR) isoforms PPARgamma2 versus PPARgamma1 and activation with retinoid X receptor agonists and antagonists" 272 : 80718076-,
40 "Hypolipi-demic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta" 94 : 43124317-, 1997
41 "Hic-5 regulates an epithelial program mediated by PPARgamma" 19 : 362375-, 2005
42 "Functional genomic analysis reveals cross-talk be-tween peroxisome proliferator-activated receptor gamma and calcium signaling in human colorectal cancer cells" 282 : 2338723401-, 2007
43 "Expres-sion of peroxisome proliferator-activated receptor-gamma in macrophage supresses experimentally induced colitis" 292 : G657666-, 2007
44 "Estrogen receptor alpha interacts with Gal-pha13 to drive actin remodeling and endothelial cell migra-tion via the RhoA/Rho kinase/moesin pathway" 20 : 175671-, 2006
45 "Endoscopic identification and quantification of aberrant crypt foci in the human colon" 56 : 657662-, 2002
46 "Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascu-lar causes" 356 : 24572471-, 2007
47 "Dose-dependent suppression of hyperlipidemia and intestinal polyp formation in Min mice by pioglitazone, a PPAR gamma ligand" 94 : 960964-, 2003b
48 "Does the inhi-bition of c-myc expression mediate the anti-tumor activity of PPARs ligands in prostate cancer cel lines?" 462 : 112-, 2007
49 "Direct thiazolidinedione action on isolated rat skeletal muscle fuel handling is independent of peroxisome proliferator-activated receptor-{gamma}-mediated changes in gene expression" 50 : 23092315-, 2001
50 "Diferentiation and reversal of malignant changes in colon cancer through PARgama" 4 : 1046-1052, 1998
51 "Diferentiation and growth inhibition mediated via the RXR:PPARgamma heterodimer in colon cancer" 240 : 225233-,
52 "Diferential expression, distribution, and func-tion of PPAR-gamma in the proximal and distal colon" 30 : 342353-, 2007
53 "Detection of aberrant crypt foci by magnifying colonoscopy" 46 : 6165-, 1997
54 "Crystal structure of the ligand binding do-main of the human nuclear receptor PPARgamma" 273 : 3110831112-, 1998
55 "Concomitant suppression of hyperlipidemia and in-testinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands" 63 : 6090-6095, 2003a
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57 "Characteristics of the peroxisome proliferator acti-vated receptor gamma (PPARgamma) ligand induced apop-tosis in colon cancer cells" 50 : 658664-, 2002
58 "Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer" 70 : 2631-2646, 2002
59 "An antidiabetic thiazolidin-edione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)" 270 : 1295312956-, 1995
60 "Altered growth of human colon cancer cel lines dis-rupted at activated Ki-ras. Science 260" 8588-, 1993
61 "Activators of the nuclear receptor PPARgamma enhance colon polyp formation" 4 : 10581061-, 1998
62 "Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice" 4 : 1053-1057, 1998
63 "Activa-tion of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells" 115 : 10491055-, 1998
64 "Aberrant crypt foci of the colon as precursors of adenoma and cancer" 339 : 12771284-, 1998
65 "APC-dependent suppression of colon carcinogene-sis by PPARgamma" 99 : 13771-13776, 2002
66 "A phase II study of troglitazone an activator of the PPARgamma receptor in patients with chemotherapy-resistant metastatic colorectal cancer. Cancer J. 8" 395399 Cancer J. : 8-, 2002
67 "4-Hydroxynonenal and PPARgamma ligands af-fect proliferation, diferentiation, and apoptosis in colon can-cer cells" 42 : 16611670-, 2007