Naringin included in citrus fruits is a flavonoid. It has antioxidant and anti-inflammatory effects. However, the low solubility and stability in lipophilic systems limit commercial applications. To overcome this problem, esterification can be employe...
Naringin included in citrus fruits is a flavonoid. It has antioxidant and anti-inflammatory effects. However, the low solubility and stability in lipophilic systems limit commercial applications. To overcome this problem, esterification can be employed. In this study, naringin oleate was synthesized through esterification using naringin and oleic acid. The optimal synthetic conditions were derived by manipulating the immobilized enzyme type, enzyme concentration, ㏖ar ratio (naringin:oleic acid), reaction temperature and solvents. Finally, over 90% conversion was obtained under optimal synthetic. Naringin oleate, a high value-added material, has higher solubility and stability in lipophilic systems than the original naringin and obtains higher physiological efficacy. Furthermore, the commercial potential of the process is expected through achieving a relatively short reaction time with high conversion.