복강경하 대장절제술을 시행 받는 환자에서 라모세트론과 온단세트론외 술 후 오심 및 구토 예방 효과 비교 = Comparision with Ramosetron and Ondansetron for Preventing Postoperative Nausea and Vomiting after Laparoscopic colectomy

다국어 초록 (Multilingual Abstract)

Objectives ： We evaluated the efficacy of ramosetron and ondansetron for preventing postoperative nausea and vomiting (PONV) in laparoscopic colectomy.
Methods and Materials ： Eighty patients who received laparoscopic colectomy were randomly divided into two groups： R group (ramosetron 0.1mg PO) and O group (ondansetron 4mg twice IV). Injection or oral medication was administered before the induction of anesthesia in each group. Injection was administered at the end of surgery in O group. General anesthesia was induced using propofol and rocuronium, and maintained with sevoflurane, remifentanil and air (FiO2 0.5), We investigated the incidences of PONV in each group by the Rhodes index of nausea, vomiting and retching (RINVR) at postoperative 6 and 24 hours.
Results ： The incidence of PONV was not different between group at each time points after surgery (at postoperative 6 hours： 20% in group R, 17.5% in group 0, at postoperative 24 hours； 12.5% in group R, 7.5% in group 0). There was no difference in the severity of PONV, satisfaction, rescue drug usage.
Conclusion ： Prophylactic therapy with ramosetron is as effective as conventional prophylactic therapy with ondansetron for preventing PONV in general anesthesia for laparoscopic colectomy.

목차 (Table of Contents)

• Ⅰ . 서론
• Ⅱ . 연구대상 및 방법
• Ⅲ . 결과
• Ⅳ . 고찰
• Referenecs