Inclusion compounds of suprofen with α- and, β-cyclodextrins (α-CyD, β-CyD) were studied in comparison with suprofen alone and commercial suprofen capsules. Inclusion compound formations of suprofen with α-, and β-CyDs in aqueous solution and in...
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https://www.riss.kr/link?id=A3042276
1985
Korean
518.000
SCOPUS,KCI등재,SCIE
학술저널
130-139(10쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
Inclusion compounds of suprofen with α- and, β-cyclodextrins (α-CyD, β-CyD) were studied in comparison with suprofen alone and commercial suprofen capsules. Inclusion compound formations of suprofen with α-, and β-CyDs in aqueous solution and in...
Inclusion compounds of suprofen with α- and, β-cyclodextrins (α-CyD, β-CyD) were studied in comparison with suprofen alone and commercial suprofen capsules. Inclusion compound formations of suprofen with α-, and β-CyDs in aqueous solution and in solid state were confirmed by UV absorption, circular dichroism spectroscopies, IR spectroscopy, differential scanning calorimetry and X-ray diffraction measurements. Solid inclusion complexes were prepared by freeze-drying method, and their molar ratios were found to be 1 : 1. The dissolution rate of inclusion complexes of suprofen with CyDs was notably higher than that of suprofen alone.
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