Bone morphogenic protein-7이 복막의 섬유화에 미치는 효과 = Effect of Bone Morphogenic Protein-7 on Peritoneal Fibrosis

국문 초록 (Abstract)

당뇨병과 고혈압의 유병률 증가, 신장 독성 물질에의 노출 기회 증가, 약물 남용 및 공해 등의 원인에 의해 전 세계적으로 만성신질환의 빈도가 증가함에 따라 복막투석의 시행도 증가하고 있다. 복막투석은 새로운 기술과 개념의 꾸준한 도입으로 혈액투석과 더불어 말기신부전 환자의 주요한 신대체 요법 중 하나로 자리 잡고 있다. 2005년 현재 우리나라 전체 투석 환자의 22.3%가 복막 투석을 받고 있으며, 홍콩은 83% 그리고 미국은 7.5%가 복막투석을 받고 있다1). 복막투석은 혈액투석에 비하여 심혈관계 안정성이 높고 잔여 신기능 유지에 있어 장점을 지니고 있으며2) 투석 시작 후 3년간 환자 생존율이 우수하나3,4) 상대적으로 낮은 기술 생존율이 문제가 되고 있다.

참고문헌 (Reference)

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